Though DNA methylation is necessary to maintain monoallelic expression of imprinted genes, it is still unclear whether it represents the primary mark. Here we ask whether the imprinting mark is still present in terminally differentiated somatic cells in which theJ ForejtV PůzaFolia Biol...
interpretation of GS results in new- borns, we curated a catalog of genes with putative pediatric relevance for their validity based on the ClinGen clinical validity classification framework criteria, age of onset, penetrance, and mode of inheri- tance through systematic evaluation of published ...
Advanced Nano Technologies(ASX:ANO.AX) (formerly Antaria Limited) is a specialist developer and manufacturer of advanced materials. These materials are used by manufacturers in the personal care, chemical and industrial sectors to add unique or competitive advantages to their end products. Advanced Nan...
Sci. U.S.A.(《美国科学院院报》) 在线发表了题为“ZFP57 dictates allelic expression switch of target imprinted genes”(ZFP57决定印记基因单等位基因表达转换机制)的研究成果。本研究首次报道了小鼠印记基因的单等位基因表达调控及其转换机制。基因组印记是存在于高等动物和植物中的一种表观遗传现象。李夏军课题...
A UNESCO World Heritage Site, Lyon has 2,000 years of history imprinted on its streets (yes, the cobblestone kind). Explore this history in Vieux Lyon (one of Europe's most extensive Renaissance neighborhoods) and Lyon's two Roman amphitheatres, which still stage rock concerts today. It's...
Innate immune responses were examined in cervicovaginal tissues by determining gene expression patterns by microarray analysis using nylon membranes imprinted with cDNA fragments coding for inflammation-associated genes. At 24 h, a wide range of genes, including those for chemokines and Th1- and Th2-...