OBJECTIVE — Insulin lispro (Humalog), a human insulin analog, has a more rapid onset, earlier peak, and shorter duration of glucose lowering activity than regular human insulin. However, it is not known whether insulin lispro crosses the human placenta and reaches the fetus. Therefore, the ...
insulin analogue, has a quick 5–15 min onset of action and peaks in 30–90 min with an effective duration of only 4–6 h (Hirsch, 2005a). This type of insulin was designed to treat diabetics enjoying a food bolus. The resulting peak in endogenous insulin ...
Duration of action of ultralente is greater, but intersubject variability is also greater than that of NPH. Glargine is a peakless insulin, it lasts nearly 24 h, it has lower intersubject variability than NPH and ultralente, and it closely mimics CSII, the gold standard of basal insulin ...
Mix 75/25 [75%insulinlisproprotaminesuspension and 25% insulin lispro injection, (rDNA origin)] injection is a combination of two man-made insulins used to treat type 1 (insulin-dependent) or type 2 (non-insulin-dependent)diabetes. The combination of insulins in Humalog Mix 75/25 starts wo...
The data in Table 1 reflect the exposure of 252 patients with type 1 diabetes to ADMELOG with mean exposure duration of 49 weeks. The type 1 diabetes population had the following characteristics: Mean age was 43 years and mean duration of diabetes was 20 years. Fifty-nine percent were male...