Duration of action may vary according to the dose, injection site, blood flow, temperature, and level of physical activity.Use: To improve glycemic control in patients with diabetes mellitus.Renal Dose AdjustmentsUse with caution; insulin requirements may be reduced in patients with renal impairment...
Insulin lispro has a more rapid onset of activity and a shorter duration of action when compared to regular human insulin while maintaining equal glucose lowering ability. Insulin lispro provides better postprandial glucose control at a more convenient time relative to consumption of a meal....
Two hundred fifty-three patients with type 2 diabetes were exposed to ADMELOG with mean exposure duration of 25 weeks. The type 2 diabetes population had the following characteristics: Mean age was 62 years and mean duration of diabetes was 17 years. Fifty-four percent were male, 90% were W...
The preclinical data from animals administered insulin lispro indicate that the hypoglycemic potency of the analog is essentially equivalent to that of regular human insulin with the benefit of a more rapid onset of activity with a shorter duration of action. In in vitro receptor binding studies, ...
OBJECTIVE: lispro is an analog of with a faster onset and a shorter duration of action than regular . Efficacy and tolerability of lispro in continuous sub... R Renner,A Pfutzner,M Trautmann,... - 《Diabetes Care》 被引量: 311发表: 1999年 Comparison on Insulin Aspart With Buffered Regula...
Basal Insulin peglispro (BIL) demonstrates hepato-preferential action vs insulin Glargine (GL) in patients with type 1 diabetes mellitus Abstracts Basal insulin peglispro (BIL) has a longer duration of action than conventional insulin analogues and a hepato-preferential mechanism of action. This study...
Basal insulin peglispro (BIL) has a longer duration of action than conventional insulin analogues and a hepato‐preferential mechanism of action. This study assessed whether BIL was non‐inferior to isophane insulin (NPH) in reducing HbA1c in insulin‐naïve patientswith type 2 diabetes, when ...
The risk of hypoglycemia after an injection is related to the duration of action of the insulin and in general, is highest when the glucose lowering effect of the insulin is maximal. As with all insulin preparations, the glucose lowering effect time course of HUMALOG Mix75/25 may vary in di...
insulin lispro is a human insulin analog of rapid onset of action and duration, which mimics the physiological insulin profile after a meal. we have evaluated the safety and efficacy of lispro insulin in comparison with human regular insulin in a crossover, multicenter, randomized trial in 25 ty...
To compare the efficacy and safety of basal insulin peglispro (BIL), which has a flat pharmacokinetic and pharmacodynamic profile and a long duration of ac... RM Bergenstal,H Lunt,E Franek,... - 《Diabetes Obesity & Metabolism》 被引量: 0发表: 2016年 加载更多来源...