Lisinopril: dose-peak effect relationship in essential hypertension. Br J Clin Pharmacol 1988; 25(5): 533-8.Cirillo VJ, Gomez HJ, Salonen J, et al. Lisinopril: dose-peak effect relationship in essential hypertension. Br J Clin Phar- macol 1988; 25: 533-538....
In patients with renal impairment (GFR <30 mL/minute), peak and trough lisinopril levels increase, time to peak plasma concentration increases, and time to attain steady state is prolonged; in patients with GFR ≥30 mL/minute, elimination half-life is minimally altered. Lisinopril removed by ...
Dosages of lisinopril are administered orally once daily, can be given at any time in relation to meals, and must be individualised. Treatment of elderly patients should be started at lower dosages than in other adults. Lisinopril should be used with caution in patients with hyperkalaemia, ren...
With greater impairment, however, peak and trough lisinopril levels increase, time to peak concentration increases and time to attain steady state is prolonged. Older patients, on average, have (approximately doubled) higher blood levels and area under the plasma concentration time curve (AUC) than...
With greater impairment, however, peak and trough lisinopril levels increase, time to peak concentration increases and time to attain steady state is prolonged [see DOSAGE AND ADMINISTRATION]. Lisinopril can be removed by hemodialysis. Pediatric Patients The pharmacokinetics of lisinopril were studied in...
With greater impairment, however, peak and trough lisinopril levels increase, time to peak concentration increases and time to attain steady state is prolonged [see DOSAGE AND ADMINISTRATION (2.4)]. Lisinopril can be removed by hemodialysis. Pediatric Patients The pharmacokinetics of lisinopril were...
anytime, but more commonly the head and neck are affected typically occurs within the first month of treatment.49Patients of African descent are 3 times more likely to be affected.50Patients with perioral swelling may present to their dentist thinking they have atooth infection; therefore, the ...
peak and trough lisinopril levels increase, time to peak concentration increases and time to attain steady state is prolonged. Older patients, on average, have (approximately doubled) higher blood levels and area under the plasma concentration time curve (AUC) than younger patients (SeeError! Hyper...
2. In guinea-pig atria, lisinopril (0.001-1 microM) exerted a negative inotropic effect which was accompanied by a shortening of the time to peak tension and time for total contraction. However, it did not modify atrial rate or the characteristics of the ventricular action potentials recorded ...
71. The sustained effect of once-daily enalapril versus lisinopril: calculation of trough-to-peak ratio from 24-h ambulatory blood pressure measurements by Fourier analysisdoi:10.1016/S0300-2977(97)87125-2H.H. Vincent and M. DiamantThe Netherlands Journal of Medicine...