phospholipid, cholesterol, PEG-lipid and an nucleic acid payload, formulated through rapid microfluidic mixing13,14. At a pH below its pKa, the ionizable lipids enable electrostatic complexation of anionic nucleic acid molecules, followed by self-assembly and buffer exchange to physiological pH to fo...
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According to SERS signal analysis, exosome PD-L1 levels in healthy donors, patients with early NSCLC and patients with advanced NSCLC could be clearly distinguished, and individual exosome PD-L1 levels could be monitored in real time before and after clinical treatment [134]. A label-free method...
Lipids are essential for signal transduction, energy metabolism and membrane structural integrity. However, excessive levels of circulating lipids have been linked to cancer malignant progression through “lipotoxicity”, which results in oxidative stress, mitochondrial dysfunction, and impaired autophagy [28...
The analysis is rapid (8 min/sample) and uses a single HPLC pump with isocratic mobile phase. The method has been adapted to study cellular and whole animal reduction of lipoate, membrane transport of lipoate and dihydrolipoate, and subeellular enzymes that reduce lipoate....
All colostrum samples were collected from healthy donkeys or cows aged 2 to 3 yr in the first 24 h after delivery. The 45 DC samples was divided into 3 groups (each group contained 15 colostrum samples), and each group was then pooled before the experiment. The grouping and mixing method...
If desired, UV radiation can act on the liquid shortly before it is brought into contact with the object to be cleaned. It is preferable for exposure to UV radiation to take place when the washing or cleaning liquid is in contact with the textile to be washed or the hard surface to be ...
1. A dual zone reverse phase packing material for liquid chromatographic columns which comprises a porous support having as an internal zone a lipophilic partitioning phase bonded to the internal surface of said porous support and having as an external zone a lipophobic phase comprising fluorocarbon ...
The hydrophilic index of surfactant system is based upon the calculation of HLB (hydrophile-lipofile balance) of surfactants. The calculation of HLB is further discussed in “Surfactants and Interfacial Phenomena” by M. J. Rosen. In this application, HLB is applied to ionic surfactants. A surfa...
the cell thickness, and the alignment layer comprises at least one lipophilizing, lipophilic and/or amphiphilic compound. The liquid crystal display according to the invention exhibits a short switching time and a significantly reduced surface memory effect, and thus achieves an improved display ...