LLPS, an intrinsic property of chromatin [91], plays a pivotal role in regulating chromatin’s structure. For example, heterochromatin is an inactive region of the eukaryotic genome [92], and its formation is driven by LLPS [93]. Moreover, transcription factors regulate the 3D structure of ...
amyloid bodies; intrinsically disordered protein; liquid–liquid phase separation; membrane-less organelle; nuclear stress bodies; nucleolar biomolecular condensates 1. Introduction In the 21st century, there have been at least two revolutionary changes in the understanding of the structural and functional ...