Liquid–liquid phase separation (LLPS) underlies the formation of membrane-free organelles in eukaryotic cells and plays an important role in the development of some diseases. The phase boundary of metastable liquid–liquid phase separation as well as the cloud point temperature of some globular prot...
Liquid–Liquid Phase Separation of Two Non-Dissolving Liquids—A Mini Review by Dragana Dimitrijević 1,*, Markus Bösenhofer 1,2 and Michael Harasek 1 1 Institute of Chemical, Environmental and Bioscience Engineering, TU Wien, 1060 Vienna, Austria 2 Area 4—Simulation and Analyses K1-MET...
liquid–liquid phase separation; intrinsic solubility; melting point; drug-like Graphical Abstract1. Introduction Intrinsic aqueous solubility (𝑆𝑐0S0c) is one of the most important physicochemical properties of a crystalline drug. Many 𝑆𝑐0S0c prediction methods have been reported in the ...
liquid–liquid phase separation (LLPS);ChatGPT;Gemini;artificial intelligence (AI) 1. Introduction Significant advancements in artificial intelligence (AI) and human–computer interaction have been achieved, particularly with the development of large language models (LLMs). AI, essentially the replication...
Keywords: amyloid bodies;intrinsically disordered protein;liquid–liquid phase separation;membrane-less organelle;nuclear stress bodies;nucleolar biomolecular condensates