The precision offered by liposome-mediated drug delivery extends beyond oncology. In infectious diseases, liposomes can be tailored to seek out specific pathogens, improving antimicrobial therapies' effectiveness. Dermatological conditions, too, benefit from liposomal formulations that can be designed to pene...
Moles E, Urban P, Jimenez-Diaz MB, Viera-Morilla S, Angulo-Barturen I, Busquets MA, et al. Immunoliposome-mediated drug delivery to Plasmodium-infected and non-infected red blood cells as a dual therapeutic/prophylactic antimalarial strategy. J Control Release 2015;210:217-29....
Objective: The present work is aimed to prove zebrafish as an in-vivo model for the study of liposome mediated drug delivery. Methods: Liposomes prepared from sesame oil and therapeutic molecules were encapsulated into liposome. The effect of liposome mediated drug delivery was studied in cardiac ...
In addition, liposomes have been extensively researched as nanocarriers for drug delivery as they allow for targeted delivery of chemotherapeutics while reducing toxicity to normal organs54, with a few such formulations having already made it into the clinic (e.g., PEGylated liposomal doxorubicin, suc...
However, one of the key roadblocks in the development of such next-generation, liposome-mediated drug delivery is determining how each liposomal formulation will affect blood circulation, biodistribution, biodegradation, and toxicity45. Because of our agent's liposomal formulation, it is feasible that ...
It is reported that by optimizing the formulation of liposomes, decrease of Pgp-mediated MDR may be achieved [55]. Since liposome-based drug delivery systems are administered systematically, their interaction with cells should be also taken into account. It is supposed that the inside surface of ...
Delivery of liposome-encapsulated simian virus 40 (SV40) DNA to African green monkey Related to been used as a probe to study liposome--cell interactions and to determine conditions which favor the intracellular delivery of liposome contents to cells. The efficiency of DNA delivery by various lipos...
Liposome-Mediated Delivery of Genes and Oligonucleotides for the Treatment of Brain Tumors 来自 Springer 喜欢 0 阅读量: 39 作者:J Zhu,Z Li,R Reszka 摘要: Brain tumors present a great therapeutic challenge due to their very poor prognosis (Mahaley et al, 1989). On the other hand, brain ...
Or stimulus-mediated fusion of liposomal constituent with target cell 7. Zeta potential Zeta meter Stability of vesicles 8. In vitro drug release study Franz diffusion cell with artificial or biological membrane Dialysis bag diffusion Determine the drug release rate from vesicle 9. pH pH Meter ...
Factors influencing the efficiency of cationic liposome-mediated intravenous gene delivery. We have characterized the relationships between the design of cationic liposomes as a gene transfer vehicle, their resulting biodistribution and processing... Y Liu,LC Mounkes,HD Liggitt,... - 《Nature ...