OBJECTIVE: Low-density lipoprotein-related receptor protein 1 (LRP1) is a multi-functional endocytic receptor and signaling molecule that is expressed in adipose and the hypothalamus. Evidence for a role of LRP1 in adiposity is accumulating from animal and in vitro models, but data from human ...
Low-density lipoprotein receptor- related protein-1 (LRP1) mediates autophagy and apoptosis caused by Helicobacter pylori VacA. J Biol Chem. 2012;287:31104-5. https://doi.org/ 10.1074/jbc.M112.387498.Yahiro K, Satoh M, Nakano M, et al. Low-density lipoprotein receptor-related protein-1 (...
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Decreased capillary expression of low-density lipoprotein receptor-related protein 1 (LRP1) has been linked to increased brain amyloid beta (Aβ) accumulation in Alzheimer's disease (AD). Aβ accumulation has also been observed in (a subset of) temporal lobe epilepsy (TLE) patients, suggesting...
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LRP1 was also antagonized by treatment with the antagonist low-density lipoprotein receptor-related protein associated protein 1 (LRPAP1). We have used PDGF-BB, a PDGFR agonist, and apolipoprotein E (ApoE), an LRP1 agonist, to stimulate the activities of PDGFR and LRP1 respectively. Knockdown...
Low-density lipoprotein receptor-related protein-1 (LRP1) in the glial lineage modulates neuronal excitability The low-density lipoprotein related protein receptor 1 (LRP1), also known as CD91 or 伪-Macroglobulin-receptor, is a transmembrane receptor that interacts ... A Faissner - 《Frontiers ...
Low density lipoprotein receptor-related protein 1 couples β1 integrin activation to degradationLow density lipoprotein receptor-related protein 1 couples β1 integrin activation to degradationLow density lipoprotein receptor-related protein (LRP) 1 modulates cell adhesion and motility under normal and path...
Low Density Lipoprotein Receptor-Related Protein-1 (LRP1) Is Involved in the Uptake of Clostridioides difficile Toxin A and Serves as an Internalizing Rece... Low Density Lipoprotein Receptor-Related Protein-1 (LRP1) Is Involved in the Uptake of Clostridioides difficile Toxin A and Serves ...