We also studied patients with ischemic heart disease (n=2495), ischemic cerebrovascular disease (n=856), and breast cancer (n=1256) versus general ... AD Kjaergaard,C Ellervik,A Tybjaerghansen,... - 《Circulation》 被引量: 185发表: 2007年 Apolipoprotein B levels, APOB alleles, and ris...
The relationship between lipoprotein(a) [Lp(a)] and restenosis after intracoronary stent implantation has never been analysed in diabetic patients. The aim of the present prospective study was to evaluate whether Lp(a) levels and apolipoprotein(a) [apo(a)] phenotypes are predictors of restenosis ...
Lipoprotein(a) [Lp(a)], a low-density lipoprotein (LDL)-like particle with a large glycoprotein, apolipoprotein(a) [Apo(a)], is covalently bound to apolipoprotein B 100 by a disulfide bridge[1]. Apo(a) genotype determines both the synthetic rate and size of the Apo(a) moiety of Lp(...
Lipoprotein(a) has two main proteins: apolipoprotein(a) [apo(a)] and apolipoporoteinB100 (apoB100).The aim of this study was to describe additional proteins on Lp(a) and links to pathways that may drive disease mechanisms.#Methods:We analyzed plasma from 10 healthy volunteers, mean age ...
Apolipoprotein B versus non-high-density lipoprotein cholesterol - And the winner is... 来自 Semantic Scholar 喜欢 0 阅读量: 11 作者: Sniderman,D A.摘要: Vascular disease is already the most common cause of death in the developed world and by 2020 will become the leading cause of death in...
Quantitation and localization of apolipoproteins [a] and B in coronary artery bypass vein grafts resected at re-operation. Lp[a] is a lipoprotein whose plasma concentration is highly correlated with cardiovascular disease. Its protein moiety, apoLp[a], consists of two large pol... GL Cushing,...
Lipoprotein (a), formed by the attachment of low-density lipoprotein to apolipoprotein(a) [apo(a)] by a single disulfide bond, is a circulating particle of uncertain physiologic function that exhibits atherogenic and pro-thrombotic/anti-fibrinolytic properties in experimental settings [3]. Plasma le...
Lipoprotein(a) has several properties that potentially could be pathogenic; it consists of an apolipoprotein B containing lipoprotein, which could directly promote atherosclerosis through cholesterol deposition in the arterial wall 8, 9, 10. Further, the lipoprotein has a covalently bound apolipoprotein(...
Lipoprotein(a), Lp(a), is a modified low-density lipoprotein particle that contains apolipoprotein(a), encoded by LPA, and is a highly heritable, causal risk factor for cardiovascular diseases that varies in concentrations across ancestries. Here, we use deep-coverage whole genome sequencing in...
Recent evidence shows that apolipoprotein (apo) B, apoB/apoA-I ratio and lipoprotein(a) are better indicators of coronary risk than the conventional lipid profile. The aim of this study was to evaluate the correlation of apoA-I and B, and lipoprotein(a) with myocardial infarction (MI). We...