The retention of apolipoprotein B (apoB)-containing lipoproteins within the arterial wall plays a major causal role in the initiation and progression of atherosclerosis. There is a single apoB molecule in all apoB-containing lipoproteins (intermediate-density lipoprotein, low-density lipoprotein (LDL)...
What proportion of this risk do Lp(a) particles carry? To answer these questions, we created a novel metric of atherogenic risk: risk-weighted apolipoprotein B. Methods: In nmol/L: Risk-weighted apoB = apoB - Lp(a) Lp(a) x 7 = apoB Lp(a) x 6. Proportion of risk captured by ...
Article: Lipoprotein(a) and apolipoprotein B plasma concentrations in hypothyroid, euthyroid, and hyperthyroid subjects
apoB = apolipoprotein B; CHD = coronary heart disease; LDL = low-density lipoprotein; Lp(a) = lipoprotein(a); SNP = single nucleotide polymorphism. For both analyses, effect sizes (beta coefficients) for the exposure (apoB) were calculated using the UK Biobank data set. Beta coefficients ...
To assess the relationship between lipoprotein (a) [Lp (a)] and lipoprotein oxidation in patients with coronary artery disease (CAD). Oxidation of apolipoprotein (apo)B-containing lipoproteins, vitamin E, carotenoids, lipid-lipoprotein levels were determined in 171 CAD and 70 non-CAD subjects. ...
select article Forty year follow-up of three patients with complete absence of apolipoprotein B-containing lipoproteins Short communicationOpen access Forty year follow-up of three patients with complete absence of apolipoprotein B-containing lipoproteins Ryan Le, Liena Zhao, Robert A. HegeleMarch–Apri...
Objective To explore the relationship between triglyceride-glucose (TG),triglyceride/high-density lipoprotein (TG/HDL),homeostasis model assessment-insulin resistance (HOMA-IR),Apolipoprotein B/Apolipoprotein A1 (ApoB/ApoA1),high-sensitivity C-reactive protein (hs-CRP) and the risk of hyperuricemia (...
Low density lipoprotein (LDL)-apolipoprotein (apo) B plays a key role in this process. Metabolic parameters of LDL-apoB such as fractional catabolic rate (FCR) and production rate help to understand the underlying pathomechanisms of elevated LDL-apoB and are usually determined with tracer ...
The joint effects of apolipoprotein B, apolipoprotein A1, LDL cholesterol, and HDL cholesterol on risk: 3510 cases of acute myocardial infarction and 9805 ... Plasma levels of apolipoprotein B (apoB), the main surface protein on LDL particles, and LDL-C, the amount of cholesterol in those ...
Lipoprotein (a) Function Lipoprotein (a) (Lp(a)), a unique lipoprotein molecule, is a spherical lipid particle very similar in structure to LDL, but with an additional apolipoprotein (a) (apo(a)) component that is covalently bound by disulfide bridges to Apo B-100. In consequence, it dif...