It also explains how living organisms obtain fatty acids, both from their diets and through metabolic breakdown of stored fats. Structure stearic acidStructural formula of stearic acid.(more) Biological fatty acids, members of the class of compounds known as carboxylic acids, are composed of a ...
DNL, also known as de novo FA synthesis, is the metabolic pathway by which FAs are generated from different carbon sources (Fig. 1). In some cancers, this anabolic process is activated [4, 7, 31], and acetyl-CoA, produced from glucose catabolism in well-oxygenated condition or from alter...
ApolipoproteinsB-48and phospholipids are added. Secretion ofchylomicronsintolymph→thoracicduct →bloodstream Acyl-CoAandacetyl-CoAshould not be confused with each other.Acyl-CoAis a collective name for allactivated fatty acids.Acetyl-CoAis theacyl-CoAofacetic acid(also known as acetate). There is ...
Also Known As: Konrad Emil Bloch Awards And Honors: Nobel Prize (1964) Show More Konrad E. Bloch (born January 21, 1912, Neisse, Germany [now Nysa, Poland]—died October 15, 2000, Burlington, Massachusetts, U.S.) was a German-born American biochemist who shared the 1964 Nobel Pr...
Increased use of medication for chronic diseases among older participants may have also influenced the decreasing level of lipids found. Lipid prevention and control in the elderly is complicated, and further studies are needed. Statins are regarded as effective drugs for lowering blood lipids, and ...
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Statins form the first-line therapy with the aim to block cholesterol synthesis, but additional lipid-lowering drugs are sometimes needed to achieve low-density lipoprotein (LDL) cholesterol target values. Furthermore, beyond LDL cholesterol, also other lipid mediators contribute to cardiovascular risk....
MK2 (map kinase 2; also known as MAPKAPK2 or mitogen activated protein kinase-activated protein kinase 2) is acti- vated by ERK. These signaling cascades are partly shown in Figs. 3–4. HSPs in turn activate transcription of antioxi- dant defense genes such as SOD2 (Mn superoxide dis-...
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Adult Manduca sexta feed very irregularly in the laboratory, and many adult males never feed. Feeding adults live longer and feeding females lay many more eggs; however, in both feeding (sugar water) and starving adults a decrease of metabolic reserves is observed. Carbohydrates disappear from hem...