Fasting for >8 h, as previously required for lipid profiles, normally only occurs a few hours before breakfast. By contrast, the nonfasting state predominates most of a 24-h cycle and better captures atherogenic lipoprotein levels. Plasma contains atherogenic lipoproteins of hepatic origin in the ...
A lipid profile is a blood test used to measure a person's cholesterol and triglyceride levels. Having a lipid profile test can...
enriched for common variants in sub-Saharan Africans, to perform GWAS for fasting serum TC, LDL-C, HDL-C, and TG in the AWI-Gen cohort based on 10,603 adults, resident in six study sites across four countries in sub-Saharan Africa34,35. This was ...
Preanalytical phase (test sampling) Fasting is not routinely required for assessing the lipid profile. Consider fasting sample when nonfasting TG are ≥4.5 mmol/L (400 mg/dL); however, this is not a requirement. Take 2–3 serial blood specimens, at least 1 week apart, to allow to...
Lipids can be of endogenous or exogenous origin and affect diverse biological functions, including cell membrane maintenance, energy management and cellular signalling. Here, we report >800 lipid species, many of which are associated with health-to-disease transitions in diabetes, ageing and inflammatio...
1f, fasting blood glucose was significantly elevated after STZ injection and presented a dramatic fall after HucMDEs (10.64 ± 0.48 mmol/l) and HucMSC infusion (10.07 ± 0.29 mmol/l) (Fig. 1f), while PBS-, HELF-, and HDE-treated T2DM rats remained persistently ...
profiled miRNAs in the plasma from 203 patients with CHD and 144 age-matched controls (126 high-risk controls and 18 healthy volunteers) and showed that miR-320e was increased in CHD patients [54]. Moreover, correlation analysis indicated that miR-320e could be a better biomarker for CHD ...
Fasting is not routinely required for determination of a lipid profile: clinical and laboratory implications including flagging at desirable concentration cut-points — a joint consensus statement from the European Atherosclerosis Society and European Federation of Clinical Chemistry and Laboratory Medicine Eur...
Diabetic cardiomyopathy is a specific type of cardiomyopathy. In DCM, glucose uptake and utilization are impaired due to insulin deficiency or resistance, and the heart relies more heavily on fatty acid oxidation for energy, resulting in myocardial lipid
From the obtained results it is confirmed that there exists a functional link between fatty acid desaturase gene polymorphism and lipid profile ststus in type-2 diabetes mellitus. Further research on how fatty acid desaturases exert its effect on triglyceride levels needs to be enumerated. This wil...