The BLUP effects that are achieved by GCTA can be used to gain the genetic value of the individuals for a given phenotype in a matched validation or test set, which means \({\widehat{g}}_{test}={w}_{test}\widehat{u}\). This feature provides us with the prediction of genetic ...
data were presented as mean ± SD, statistical significance was analyzed using one-way ANOVA with Dunnett’s multiple comparisons test. Exactpvalues are provided as source data. Source data are provided as a source data file. KO, knockout; DKO: double knockout. ...
Our results demonstrated otherwise, this could be likely due to the fact that the Australian study only included AD patients while in our study, we found that the contrast between the sphingoid bases was made more evident as we compared the sphingolipid profile of AD against VaD, and the ...
The data obtained were analyzed using SPSS 22.0, and the student t--test was performed at P < 0.05 for comparison of means. Results: The mean plasma TC and LDL--c values for males were significantly lower than females values of 3.865 ± 0.675 mmol/L versus 4.251 ± 0.851...
(e.g.,a drying chamber). Alternatively, a fluid bed coater can be used for that step, as this prevents the formation of agglomerates. The α→β transformation causes the formation of fractal structures and the alteration of the dissolution profile before and after maturing (64,66,146). A...
In addition, our results showed that XKY treatment significantly diminished hepatic lipid deposition and steatosis accompanied by improved liver function (ATL and AST), lipid profile (TC and TG) and inflammation (TNF-α and IL-6) in db/db mice. The active ingredients of the individual herbs ...
(i.e., response factor) dimensions and the extent of its applicability to the global profile. Where successful, datasets aligned using a common RM can enable a higher degree of comparability and increased statistical power leading to more confidence in the biological knowledge gleaned from combined...
Critically for treatment, this diversity within the cell pop- ulation means that while cells from one microenviron- ment or cellular state may respond to a therapy, others may not, resulting in therapeutic resistance of the overall tumor. Lipid metabolism is abnormally regulated in gliomas ...
5a). For 353 of the 419 HRMS-assessed lipids (84%), the intensity profile spanning the brain regions correlated positively and significantly with at least one marker gene expression profile (cell-type-associated lipids, Pearson’s R > 0.5, p < 0.01; Supplementary Data 2). The ...
The iPSC-HLCs have previously been shown to closely mimic gene expression and lipidomic profile of primary human hepatocytes (PHHs)11, and here we aimed to study whether the miRNA profiles of iPSC-HLCs would differ between the CAD patient groups, and reflect their phenotype. Materials and ...