, the Stage 2 analysis was restricted to the ~14M SNPs that were present in the AWI-Gen study. This difference, despite the use of the same imputation panel, was due to a more stringent MAF cut-off (MAF > 0.01) compared to that used in Gurdasani et al.7(MAF > 0.005). ...
Objective: The purpose of this study was to determine the effect of the ethanol extract of Jatropha curcas leaves (EEJCL) on blood pressure, LDL levels, and HDL levels in hypertensive rats given a high-fat diet. Methods: This study is an experimental study...
We investigate gene–sleep duration interaction effects on blood lipid levels as part of the Gene-Lifestyle Interactions Working Group within the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium27,28. To permit the detection of both such sleep-duration–SNP interactions...
Genomic DNA was extracted either from saliva or blood samples. Genotyping was conducted in two batches on 3492 children using the UK Biobank Axiom 196-Array from Affymetrix (Santa Clara, USA). We applied extensive quality control metrics to the data following the recommendations of Weale M19, bas...