The compound has the same kind of lipid-lowering activity that natural thyroid hormone has when it activates receptors in the liver. The prodrug reduces cholesterol and triglyceride levels in mice without side effects.EBSCO_bspChemical & Engineering News...
High cholesterol levels are a major risk factor for CVD and lipid﹍owering drugs(LLD) have proven to reduce this risk but are also associated with multiple side effects. Frail older patients, among them patients with cognitive impairment, are possibly less likely to experience benefit from LLD ...
Lastly, two other classes of lipid-lowering drugs include fibrates and nicotinic acid, but most agree that the side effect profile precludes their use in children except in extreme circumstances. Overall, therapeutic options to lower cholesterol levels in children are expanding. 展开 关键词:...
they are used for treating patients with heterozygous and homozygous familial hypercholesterolemia (HeFH and HoFH) and as combination therapy with other lipid-lowering drugs in patients with atherosclerotic cardiovascular
Many drugs besides lipid-lowering drugs affect serum lipid levels in either a potentially harmful or beneficial way, and may therefore increase or decrease the risk of cardiovascular disease. Diuretics, β-blocking agents, progestogens, combined oral contraceptives containing ‘second generation’ progesto...
Regarding patient-related factors, it is important to highlight the potential role of side effects and polypharmacy; indeed, patients at high CV risk usually need several drugs (e.g. anti-hypertensive, anti-diabetic and anti-platelet drugs). This was also true for the patients included in the...
Different types of lipid-lowering drugs are widely used, many of which should be used long-term and have various adverse side effects, such as hepatotoxicity, renal toxicity, and neurotoxicity10–12. However, it is still a challenge to develop more effective lipid-lowing drugs with fewer ...
The methodology of a retrospective study of the side-effects of the most prescribed lipid lowering drugs, essentially fibrates, is described. This study co... AI French - 《Thérapie》 被引量: 11发表: 1991年 Determination of 37 drugs illegally added in weight-losing, lipid-lowering and laxativ...
The trials were heterogeneous in terms of inclusion criteria, type of drugs used and outcomes measured. Lipid-lowering therapy produced a marked but non-significant reduction in mortality (odds ratio 0.21, 95% confidence interval 0.03 to 1.17), but little change in non-fatal events (odds ratio ...
(redirected fromLipid-Lowering Drug) Category filter: AcronymDefinition LLDDoctor of Laws LLDLast Line of Defence(gaming clan) LLDLamb Lies Down on Broadway(band Genesis album/tour) LLDLearning Lab Denmark LLDLeft Lateral Decubitus LLDLipid-Lowering Drug ...