While there are numerous active mechanisms controlling which molecules cross a cell's plasma membrane to enter the cytoplasm, these are not the only routes by which molecules can enter cells. In fact, transport by passive diffusion across the lipid bilayer of the plasma membrane represents a ...
Additional experiments showed that lipids could spontaneously form a bilayer when mixed with water (Figure 1). Together, these observations suggested that there may be a simple explanation for the results with the red blood cells. The plasma membrane of these cells likely consists of adouble layer...
lipids not only build the continuous barrier that confers identity to every cell and organelle, but they are also active actors that modulate the activity of the proteins immersed in the lipid bilayer. The plasma membrane H+-ATPase, an enzyme from plant cells, is an excellent...
The cell plasma is a composite type of material that is made up of a two-dimensional liquid crystal (lipid–protein bilayer) to which a macromolecular network (the cytoskeleton) is loosely coupled. The latter may be approximately two dimensional as in the case of the erythrocytes or may ...
A fundamental feature of cellular plasma membranes (PMs) is an asymmetric lipid distribution between the bilayer leaflets. However, neither the detailed, comprehensive compositions of individual PM leaflets nor how these contribute to structural membrane asymmetries have been defined. We report the distinc...
membrane, but the lipid bilayer effectively repels the many large, water-soluble molecules and electrically charged ions that the cell must import or export in order to live. Transport of these vital substances is carried out by certain classes of intrinsic proteins that form a variety of ...
Mathematical modelling of lipid transbilayer movement in the human erythrocyte plasma membrane Brumen M, Heinrich R, Herrmann A, et al: Mathematical modelling of lipid transbilayer movement in the human erythrocyte plasma membrane. Eur Biophys J ... M Brumen,R Heinrich,A Herrmann,... 被引量: ...
The effect of LM fibroblast plasma membrane phospholipid composition on the selectivity of charged amphipathic anesthetics for exofacial or cytofacial leaflets was examined. Because preference of charged amphipaths for one of the plasma membrane bilayer leaflets may be conferred by net changes in the po...
Our view of biological membranes has evolved dramatically over the last few decades. In the bilayer model from Singer & Nicholson (Science 1972;175:720731)... JB Helms,C Zurzolo - 《Traffic》 被引量: 336发表: 2010年 Lipid Rafts and Apical Membrane Traffic Lipid rafts are dynamic assemblies ...
(DG), precursors for TG synthesis; DG acyltransferase (DGAT), on the other hand, determines the final stage of TG biosynthesis, catalyzing DG acylation. The newly synthesized TG molecules are then directed by the ER lipid bilayer to form cytosolic lipid droplets or can be directly excreted ...