Lipids and lipid-like molecules in cellular proliferation and differentiation: Potential in cancer chemoprevention and treatment 来自 ResearchGate 喜欢 0 阅读量: 911 作者:H. Wang,S. Chakrabarty 摘要: Lipids are integral cellular components of living organisms and play critical roles in regulating normal...
Lipids serve a great variety of functions, ranging from structural components of biological membranes to signaling molecules affecting various cellular functions. Several of these functions are related to the unique physico-chemical properties shared by all lipid species, i.e., their hydrophobicity. The...
Type 2 diabetes mellitus (T2DM), one of the main types of Noncommunicable diseases (NCDs), is a systemic inflammatory disease characterized by dysfunctional pancreatic β-cells and/or peripheral insulin resistance, resulting in impaired glucose and lipid metabolism. Genetic, metabolic, multiple lifestyl...
Various saturated and unsaturated fatty acids are the lipid components of fats, where they are bound to glycerol to form triglyceride esters (seeFig. 2 for examples of chemical structures of lipid molecules). In waxes, fatty acids are esterified with long-chain alcohols instead of glycerol. In ...
athis is not real love but i'll do anything for you just like your girlfriends. 这不是真正的爱,而是我将做任何东西为您象您的女朋友。[translate] aactruely actruely[translate] akoolhydraten 碳水化合物[translate] a我认为我再也不会忘记这些词了,因为这些词的记忆是经过了思考的过程。不再是简单...
This is characterized by increased lipid uptake, lipid synthesis, fatty acid oxidation (FAO), and lipid storage. Mounting evidence demonstrated that lipids play a critical role in cancer progression by serving as energy sources, membrane structures, signaling molecules (including bioactive lipids like ...
To determine if the changes in the concentrations of the various amino acid and lipid metabolites are directly related the clonal plasma cells in the BM, we sought to determine if there was a direct positive or negative correlation between the absolute concentration of these metabolites with the ...
the simulation of raft-like bilayers demonstrates the perturbing effect of increasing PUFA concentrations on cholesterol molecules. The force field derivation is consistent with the AMBER philosophy, meaning it can be easily mixed with protein, small molecule, nucleic acid, and carbohydrate force fields...
interaction with different types oflipid membranes. Thebacterial proteinis unique as it has the potential to recrystallize on different type of lipid structures such as liposomes, lipid bilayers, and monolayers. Interaction with saturated, unsaturated, charged, and uncharged lipid molecules was studied....
Moreover, lipid synthesis can provide signaling molecules associated with cell survival [137]. In the bone marrow microenvironment, lipid metabolism plays an indispensable role in normal HSCs, leukemia cells, LSCs, and immune cells (Fig. 5a-d). The bone marrow microenvironment is an adipose-rich...