absorption of lipids.We also found that PGL could reverse the reduced tight-junction protein expression due to intestinal lipid overload,promote Occludin and Claudin4 expression in the small intestine,and enhance the intestinal mucosal barrier.In conclusion,we demonstrated that PGL can inhibit lipid ...
Lipid metabolism disorder is a physiopathological event characterized by the abnormal synthesis, breakdown, digestion, absorption and transport of lipids in the body, resulting in excessive or insufficient lipids in various tissues and thus affecting body functions. ...
absorption process. The role of phospholipase in facilitating cholesterol absorption can be inferred from earlyin vitroorgan culture experiments, which showed that increasing phospholipid content of bile salt mixed micelles retarded cholesterol transport to the intestine. Subsequent studies also showed ...
(black triangle). Huh7 cells transfected with the indicated reporter plasmid were treated with serial-dilutions of AM580 for 24 h. For virus infection assays, AM580 was added after virus absorption; for luciferase assay, AM580 was added 6 h after plasmid transfection. Student’st-test ...
J.: Fine structural observations of the absorption of lipid particles in the small intestine of the rat. Anat. Rec. 152 , 325–350 (1965).J. Rostgaard, R.J. Barrnett, Fine structural observations of the absorption of lipid particles in the small intestine of the rat, Anat. Rec. 152...
Nanomedicines suffer from poor drug loading and uncontrolled ‘burst release’ after administration. Combining prodrug strategies with nanostructured carriers can help to overcome these limitations by improving diffusion through biological barriers, enzymatic activation of the lipid conjugate in the diseased are...
lipid absorption and metabolic pathways, potentially contributing to the development of metabolic diseases such as obesity [4,5]. The causal role of gut microbiota in host lipid metabolism dysregulation is best demonstrated in germ-free mice where they develop obesity when colonized with “obese micro...
D. absorption of lipids; E. energy storage. 38. Which is the smallest lipoprotein particle? A. Chylomicrons; B. VLDL; C. HDL; D. IDL; E. LDL. 39. In atherosclerosis disease, the levels of which compound is elevated in the blood? A. TAG, B. phospholipids; C. sphingolipids; ...
Do dietary fatty acids regulate the mechanism of intestinal lipid absorption? The other question to solve is to know how the small intestine, which secretes VLDL-like lipoproteins in the fasting or interprandial state, shifts to the secretion of larger CM particles, and thus becomes able to abso...
Absorption and lymphatic transport of cholesterol in the rat. J. Lipid Res. 9, 596–601 (1968). CAS PubMed Google Scholar Turley, S. D. & Dietschy, J. M. Sterol absorption by the small intestine. Curr. Opin. Lipidol. 14, 233–240 (2003). CAS PubMed Google Scholar Altmann, S...