Phospholipase D Activity Is Required for Actin Stress Fiber Formation in Fibroblasts Trypanosomatidssuperoxide dismutasePhospholipase D (PLD) is a ubiquitously expressed enzyme of ill-defined function. In order to explore its cellular actions,... Y Kam,JH Exton - 《Molecular & Cellular Biology》 被...
This may be the first step in the fat digestion (12). In view of these known facts, it was of interest to study whether lingual lipase activity is present in gastric and duodenal contents from patients with cystic fibrosis and, if so, if this activity could be of for the lipid digesti...
Appropriately, a large number of assays have been developed to analyze their activity in vitro. Here, we present an overview of these enzymes, along with protocols for common assays performed in solution. An emphasis is placed on assays for enzymes that can hydrolyze triacylglycerols.关键词:...
It is reasonable that this might control β-cell IP7 levels, since insulin stimulation in other tissues was shown to increase the levels of the inositol pyrophosphate [20]. Thus we interrogated IR signaling as a basis for the high IP7 levels in β-cells. Among cell lines that are a ...
Detection of lipase activity in human serum based on a ratiometric fluorescent probe Acute pancreatitis results in major mortality and morbidity. Lipase is a vital biomarker of acute pancreatitis in the early stage. Developing a simple and convenient methodology for monitoring the lipase activity is of...
KINDHERB is a hightech enterprise specializing in and developing plant extracts. Since now we have already more than 10 years experience. We are committed to the development and development of traditional Chinese herbal medicine, with strict GAP raw material base, GMP production anagement and IS...
Despite the high similarity between these secretory PLA2s,it is still not clear if these toxins can really be employed as an experimental model to predict the interactions that occur with the human PLA2HGIIA and its inhibitors. Thus, the present study aims to compare and evaluate, by means ...
HSL has been shown to have acylglycerol and cholesteryl ester hydrolase activity in the small intestine (6). Indeed, we have recently shown that deficiency of intestinal HSL modulates cholesterol but not TG metabolism in the small intestine (8). Rat iPTL is regulated by dietary fat and has ...
Herein we define lysosomal acid lipase A (LIPA) as a viable molecular target in TNBC and identify a stereospecific small molecule (ERX-41) that binds LIPA. ERX-41 induces endoplasmic reticulum (ER) stress resulting in cell death, and this effect is on target as evidenced by specific LIPA ...
These reactions usually proceed with higher regio- and/ or enantio-selectivity, thus making lipase an important biocatalyst in organic chemistryThis book will provide an insight into recent advancements and comparative account of novel lipase of Bacillus coagulans . The present book is divided into ...