The reference range for 56 clinically healthy dogs assayed by the kinetic method was 90 to 527 U/L. Diseases associated with a greater than twofold elevation in serum lipase activity as determined by the kinetic method included pancreatitis, gastritis with liver disease, and oliguric renal failure...
1, MAGL plays a critical role in lipid signalling: i) it is the major enzyme that controls the levels of 2-AG, an important lipid with various neuroprotective effects; ii) inactivation of MAGL induces an elevation in brain levels of 2-AG and a reduction of AA, a key precursor of pro-...
while commercial MH-EC released completely within about 1 h in abdominal environment (pH 6.8). Pharmacokinetic study had been done in beagle dogs compared to the commercial MH-EC. The durations of blood MH concentration above 2 μg/mL had been 9 h for MH-MNPs-EC versus 2 h for commercial...
Is this effect due to the upregulation of CB2 expression, as recently found in microglia [23]? Or is it due to elevation of the levels or activity of endocannabinoids, and in particular 2-AG, as shown in keratinocytes and brain neurons [20, 22], given the much higher efficacy of this...
A survey of serum lipase in patients suspected of having pancreatitis was performed using a one hour and a five hour incubation method. Elevation of both lipase and amylase activity in serum correlated with the presence of early acute pancreatitis. Although correlation with amylase activity was ...
MAINTAINING THE HEALTH OF DOGS AND CATS BY PROVIDING WHOLESOME, NUTRITIONAL DIETS IS BECOMING AN IMPORTANT COMPONENT OF RESPONSIBLE PET OWNERSHIP. BESIDES COMPLETE AND BALANCED NUTRITION, PRODUCT SAFETY AND QUALITY PARAMETERS, IN CONNECTION WITH TRACEABILITY, ARE BECOMING MORE IMPORTANT. The primary role...