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Diagnostic testEquine pancreatitis has no reliable ante-mortem test and is considered rare. The l,2-o-dilauryl-rac-glycero-3-glutarate-(6'-methylresorufin) ester (DGGR) lipase assay is specific for pancreatic lipase (PL). It was developed for humans and validated in dogs, cats and rats as...
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It has recently been shown by immunolocalization that pancreatic lipase is only in pancreatic acinar cells in clinically healthy dogs, suggesting that classical pancreatic lipase may be an ideal marker for function and pathology of the exocrine pancreas (Steiner et al., 2002). This hypothesis has b...
while commercial MH-EC released completely within about 1 h in abdominal environment (pH 6.8). Pharmacokinetic study had been done in beagle dogs compared to the commercial MH-EC. The durations of blood MH concentration above 2 μg/mL had been 9 h for MH-MNPs-EC versus 2 h for commercial...
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Increased PEA levels were also found in the skin of dogs with atopic dermatitis [6]. On the other hand, decreased PEA levels were reported in granuloma in rats, a model of chronic inflammation sustained by neoangiogenesis [7], and in spinal and supraspinal brain regions involved in ...
PL range was determined in healthy horses and in pancreatitis cases. PL is an inexpensive, highly-effective biomarker with the highest tissue activity and specificity of routine biomarkers. Equine pancreatitis occurs with a high prevalence and severity similar to that in dogs and cats, and in ...