6 to 17 years of age, diarrhea was the most common adverse reaction in 72 mcg LINZESS-treated patients in the FC double-blind placebo-controlled trial. Severe diarrhea was reported in one LINZESS-treated patient. If severe diarrhea occurs, dosing should be suspended and the patient rehydrated....
Dosing informationUsual Adult Dose for Irritable Bowel Syndrome with Constipation (IBS-C):290 mcg orally once a day Use: Treatment of irritable bowel syndrome with constipation (IBS-C)Usual Adult Dose for Chronic Idiopathic Constipation (CIC):...
If severe diarrhea occurs, suspend dosing and rehydrate the patient. Patient Counseling Information Advise the patient to read the FDA-approved patient labeling (Medication Guide). Advise patients: Diarrhea To stop LINZESS and contact their healthcare provider if they experience unusual or severe abdom...
If severe diarrhea occurs, suspend dosing and rehydrate the patient. Patient Counseling Information Advise the patient to read the FDA-approved patient labeling (Medication Guide). Advise patients: Diarrhea To stop LINZESS and contact their healthcare provider if they experience unusual or severe abdom...
If severe diarrhea occurs, suspend dosing and rehydrate the patient. (5.2) Adverse Reactions/Side Effects Most common adverse reactions (≥2%) reported in adult patients with IBS-C or CIC are: diarrhea, abdominal pain, flatulence and abdominal distension. (6.1) Most common adverse reaction (...