Katie has a PhD in Microbiology and has experience preparing online education content in Biology and Earth Science. Genes that are located near each other on a chromosome are called linked genes. They are linked because they travel together during meiosis. This means they get packaged into the ...
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According to the rate of living theory, metabolic rate is linked to lifespan. Consequently, we could hypothesize that gene function (specifically, the proportion of oxic genes) is also associated with lifespan. To test this hypothesis, we used data on the lifespan of 30 organisms, including 2...
aGraphical abstract showing the samples and analysis created in BioRender.bUpSet plot showing the number of differentially expressed genes (FC cutoff of 1.2 andp-adj<0.05) that are unique to each tissue and overlapping different tissues. The liver had the highest number of unique genes while adre...
Here, we use a microarray approach to show that male chicken embryos generally express higher levels of Z-linked genes than female birds, both in soma and in gonads. The distribution of male-to-female fold-change values for Z chromosome genes is wide and has a mean of 1.4–1.6, which is...
The platelet αIIbβ3 complex is a member of the integrin family of receptors, each of which is composed of an α and a β subunit derived from separate genes. αIIbβ3 is important in platelet function, and both qualitative and quantitative disorders of αIIbβ3 result in the bleeding di...
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Thousands of mammalian promoters are defined by co-enrichment of the histone tail modifications H3K27me3 (repressive) and H3K4me3 (activating) and are thus termed bivalent. It was previously observed that bivalent genes in human ES cells (hESC) are frequ
3B). Among the genes overexpressed in the opercular regions related to brain growth, we found DIO3, which deactivates T4 to T3 conversion; NTF3, involved in the formation of thalamocortical connections and neurite growth and survival and IRX2, involved in developmental pattern formation. For ...
1, we give a more concrete real-world example on the use of Semantic Web technologies for representing data in the Kyoto Encyclopedia of Genes and Genomes (KEGG) — an integrated data source consisting of several databases, broadly categorized into biological pathways, proteins, and drugs9 –and...