Edgotype: a fundamental link between genotype and phenotype. Curr. Opin. Genet. Dev. 23, 649-657 (2013).Sahni N , Yi S , Zhong Q , Jailkhani N , Charloteaux B , Cusick ME , Vidal M ( 2013 ) Edgotype: a fundamental link between genotype and phenotype . Curr Opin Genet Dev ...
Cornish-Bowden, A. and Cárdenas, M.L. 2000. From genome to cellular phenotype: a role for metabolic flux analysis? Nature Biotechnol. 18: 267–268. Google Scholar Cornish-Bowden, A. and Eisenthal, R. 2000. Computer simulations as a tool for studying metabolism and drug design. In: A....
Edgotype: the link between genotype and phenotype. Current opinion in genetics & development. 2013; 23:649-657.Fiehn, O. (2002). Metabolomics--the link between genotypes and phenotypes. Plant Molecular Biology, 48, 155-171... O Fiehn 被引量: 454发表: 2017年 Preprocessing, classification mo...
Confronting complexity in late‐onset Alzheimer disease: application of two‐stage analysis approach addressing heterogeneity and epistasis A new comprehensive statistical and computational strategy for identifying the missing link between genotype and phenotype has been proposed, which emphasizes ... TA ...
The relationship betweengenotypeand phenotype is essential to understand how biological evolution proceeds. The distinction between the hereditary and developmental pathways as causally separated processes dates back to 1911 (Johannsen1911): the genome is inherited, while the phenotype is its final... ...
elegans. This work describes a potential crosstalk between AD and HIV/AIDS via the cross-seeding between Aβ and SEVI, identifies SEVI as Aβ inhibitor for possible treatment or prevention of AD, and explains the role of SEVI in the gender difference in AD....
By building on these technological breakthroughs, it may become possible in the future to bridge the genotype–phenotype gap and tackle the long-standing question of how diverse body plans are genetically encoded68. We provide EmbryoNet as open-source software, with Python packages, a GitHub ...
Using model organisms in an undergraduate laboratory to link genotype, phenotype, and the environmentmodel organismszebrafishCelegansundergraduateeducationWe developed laboratory exercises using zebrafish (Danio rerio) and nematodes (Caenorhabditis elegans) for a sophomore-level Integrative Biology Laboratory ...
A chondrodysplasia family produced by mutations in the diastrophic dysplasia sulfate transporter gene: genotype/phenotype correlations Am J Med Genet, 63 (1996), pp. 144-147 View in ScopusGoogle Scholar 21 P. Kraulis A program to produce both detailed and schematic plots of proteins J Appl Crys...
Kerem, E., Corey, M., Kerem, B. S., Rommens, J., Markiewicz, D., Levison, H., Tsui, L. C., & Durie, P. (1990). The relation between genotype and phenotype in cystic fibrosis–analysis of the most common mutation (delta F508).(22), 1517–1522. doi:10.1056/NEJM199011293232203...