conjoin,join- make contact or come together; "The two roads join here" Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc. Want to thank TFD for its existence?Tell a friend about us, add a link to this page, or visitthe webmaster's page ...
a, Scatter plot of log2stable isotope labelling by amino acids in cell culture (SILAC) ratios of SILAC-based quantitative interaction proteomics of pSer2-modified RPB1 across two independent experiments, including a label swap. Pol II-interacting proteins were compared between mock-treated cells and...
Proteins covalently attached to DNA, also known as DNA–protein crosslinks (DPCs), are common and bulky DNA lesions that interfere with DNA replication, repair, transcription and recombination. Research in the past several years indicates that cells possess dedicated enzymes, known as DPC proteases,...
To test this further, we selectively blocked the N-terminal Cys2 with formaldehyde, which reacts more efficiently with cysteine than other amino acids to form a thiazolidine ring (40, 41, 42, 43) (Fig. 2D). Our proposed mechanism predicts that the α-NH2 group of Cys2 initiates DPC form...
proteins. Among the chemical cross-linkers, aldehyde-derived agents such as glutaraldehyde, formaldehyde, epoxy resins, and glyoxal have been highly investigated to improve the water resistance properties of protein films (Zhang, Li, et al., 2021). ε-amino group of lysine is considered the ...
PARP-1 binds to the C-terminal-100 amino acids of NEIL1 and NEIL1 binds to the BRCT domain of PARP-1. NEIL1 stimulates the poly(ADP-ribosyl)ation activity of PARP-1. Furthermore, NEIL-deficient fibroblasts have impaired poly(ADP-ribosyl)ation of cellular proteins after DNA damage, which...
(more simply, can you explain the similarity and differences in the bonding in polyamides versus polypeptides/proteins ?)Clive a) structure of CONH, it is the bridging link as the CO from the carboxyl acid and the NH from diamine join together CO-NHHC=O N b) the groups are carboxylic ...
An antibody in this form is not acceptable for conjugation because the biotinylation reaction targets amino acids on the antibody that would also be found in the other proteins. Your biotin/streptavidin assay would then be detecting, not only the activity of the IgG antibody, but also the ...
and heliorhodopsins (light-sensitive receptor proteins that can be used as proton channels by giant viruses during infection33). Together, biogeographic patterns, functional gene repertoires and metatranscriptomic signal indicate that mirusviruses influence the ecology of key marine eukaryotes using a previ...
2). Following this assumption, we tried to stabilize the unsolved conformation of design-1 by introducing amino acid residues conserved in Phs018, a RIFT protein. Phs018 has high two-fold symmetry and likely retains the properties of the ancient RIFT-fold proteins5. Phs018 has remarkable ...