As another example,try looking at the graph below. The height of the line is always 2, which means that the difference in height (even between two points on either side of the graph, y1 and y2) will always be 0. So: slope=y2−y1x2−x1=0x2−x1=0 ...
Despite the overlap in substrate recognition (Table 15.1), differences between individual transporters include tissue distribution and substrate preference. Thus, these ABC transporters are not functionally redundant molecules. Pgp is considered to prefer large hydrophobic, either uncharged or slightly ...