To determine whether Dapagliflozin 10mg-Linagliptin 5mg (group 1) is associated with an improved glycemia compared with Linagliptin (group 2) alone in uncontrolled on metformin monotherapy.Method: In a Phase 3, randomized, double blind, active-controlled, double dummy study, a total of 232 T2DM ...
Define linagliptin. linagliptin synonyms, linagliptin pronunciation, linagliptin translation, English dictionary definition of linagliptin. n. An oral hypoglycemic drug, C25H28N8O2, used to treat type 2 diabetes. American Heritage® Dictionary of the E
Saxagliptin/Dapagliflozin: A Review in Type 2 Diabetes Mellitus Article 07 February 2017 Alogliptin: A Review of Its Use in Patients with Type 2 Diabetes Mellitus Article 09 April 2015 References Davidson JA. Advances in therapy for type 2 diabetes: GLP-1 receptor agonists and DPP-4 inhib...
Acta Clin Belg (2003) J. Rosenstock et al. Dual add-on therapy in poorly controlled type 2 diabetes on metformin: randomized, double-blind trial of saxagliptin + dapagliflozin vs saxagliptin and dapagliflozin alone Diabetes Care (2015)View more referencesCited by (16) ...
Separation was carried out on Symmetry® C18 column using methanol: 10 mM ammonium formate buffer (containing 0.2% formic acid) in a ratio of (95: 5, v/v) as mobile phase at flow rate 0.25 mL min−1. Quantification was performed with multiple reaction monitoring in positive ...
Patients with T2DM, with a stable dose of metformin ≥1000 mg/day as monotherapy for at least 3 months before screening, with inadequate glycemic control at screening were randomly assigned to either arm A (dapagliflozin 10 mg + linagliptin 5 mg) or arm B (linagliptin 5 mg) in a 1:1 ra...
Materials and Methods: A total of 235 patients with inadequate response to metformin (≥1000 mg/day) plus linagliptin (5 mg/day) were randomized to receive either dapagliflozin/linagliptin fixed‐dose combination (FDC [AJU‐A51]) 10/5 mg/day (n = 117) or linagliptin 5 mg plus p...