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When the elasticities are known, a full dynamic model of the whole metabolic network can be set up using linlog kinetics. Such a model allows in principle the calculation of control coefficients also under dynamic conditions. In linlog kinetics, the elasticities are the kinetic parameters represent...
The structure was solved by direct methods using SHELXT [32] and refined by full-matrix least-squares fitting on F2 using MoPro program [33]. All non-hydrogen atoms were refined anisotropically. The hydrogen atoms were refined isotropically using X-H bond length restraints and X-H distance ...
As usual, the upper limit of the integration is infinite; it is not convenient to identify the parameters of the model, and thus we used a discrete form of the model to replace the integration. The discrete form of the MRPIM can be written as y(t) = p1V(t) + p2V(t)2 + p3V(...