Oxidative stress is a component of many diseases, including atherosclerosis, chronic obstructive pulmonary disease, Alzheimer disease and cancer. Although numerous small molecules evaluated as antioxidants have exhibited therapeutic potential in preclini
Vegetative and flower morphology of the characters evaluated: (A) creeping habit inAnathallis; (B) caespitose habit with longer inflorescences than leaf inPseudolepanthes; (C) proliferating ramicauls inTubella; (D) ornamented lepanthiform bracts inTrichosalpinx; (E) laminar, motile lip (I) o...
With the discovery of existing circulating cell-free fetal DNA (ccffDNA) in maternal plasma and the advent of next-generation sequencing (NGS) technology, there is substantial hope that prenatal diagnosis will become a predominately non-invasive process
Drug discovery in the late twentieth and early twenty-first century has witnessed a myriad of changes that were adopted to predict whether a compound is likely to be successful, or conversely enable identification of molecules with liabilities as early as possible. These changes include integration ...
University students are a population of special interest with regard to these problems because they are ‘digital natives’, who have grown up surrounded by technology and have never known a world without the internet (Anderson et al.,2017), and need such technology for their optimal academic, ...
Mass spectrometry (MS) techniques, because of their sensitivity and selectivity, have become methods of choice to characterize the human metabolome and MS-based metabolomics is increasingly used to characterize the complex metabolic effects of nutrients or foods. However progress is still hampered by ...
The possibilities of surgical treatment are often underestimated. A multi-centre database (PelvEx Collaborative) was established to collect data and experiences to optimize the research in this field. Keywords: pelvic exenteration; exenteration surgery; multivisceral surgery; pelvic malignancies; advanced ...
1.1. The Fluvial Anthroposphere in the Context of the Global Anthropocene Over the last decade, the Anthropocene has become a key scientific concept. It can be considered as a geological time scale that features significant and synchronous anthropogenic-induced changes in climate and material cycles,...
Biodegradable and bioabsorbable synthetic materials, such as the polyester family of degradable polymers, have tunable compressive strength, controllable degradation rates and improved biocompatibility, which has led to their widespread adoption for biomedical applications [26,27]. Polylactic acid (PLA), pol...
Tumor RNA: For each dog, the tumor was dissected into approximately 3 mm by 3 mm samples, flash frozen in liquid nitrogen, and stored at −80 °C until RNA extraction. RNA isolation was accomplished using a homogenizer in combination with acid guanidinium thiocyanate-phenol-chloroform extraction...