产品介绍 :The ABLIM1 protein has an N-terminal domain that contains four double zinc finger motifs, which conform to the LIM motif consensus sequence. ABLIM1 binds to F-Actin through a dematin-like domain and is expressed in retina, brain and muscle tissue. There are four known isoforms ...
The LIM domain is a modular protein-binding interface that is found in a wide variety of eukaryotic proteins with diverse biological functions. The LIM domain can be identified by a conserved sequence: C(X)2C(X)16–23(H/C)X2,4(C/H/E)(X)2C(X)2C(X)14–21(C/H)(X)2/1/3(C...
specificity. Despite their structural similarity to GATA-type, DNA-binding zinc-fingers LIM domains do not bind DNA and instead mediate protein–protein interactions[31]. In proteins with multiple LIM domains, each LIM domain is connected by a flexible linker, with no preference in the spatial or...
Although individual transcription factors initiating progression remain unknown, LIM-only protein (LMO) and LIM-domain binding protein (LDB) negatively regulate breast carcinoma cell differentiation. In this study, we investigated the expression of LMO4 and LDB in squamous cell carcinomas of the oral ...
别名C terminal LIM domain protein 1; C-terminal LIM domain protein 1; Carboxy terminal LIM domain protein 1; CLIM 1; CLIM1; CLP 36; CLP36; Elfin; Enigma; Enigma homolog; hCLIM 1; hCLIM1; LIM domain protein CLP 36; LIM domain protein CLP-36; LIM domain protein CLP36; PDLI1_HUMAN...
LIM domain-bindingprotein 1or LIM-domain binding 1 (Ldb1) (Agulnick et al., 1996), also known as nuclear interactor (NLI) (Jurata, Kenny, & Gill, 1996) or CLIM2 (Bach, Carrière, Ostendorff, Andersen, & Rosenfeld, 1997), was identified by protein–protein interaction screening using ...
Turner;J;Nicholas;H;Bishop;D;Matthews;J;M;Crossley;M.The LIM protein FHL3 binds basic Kruppel-like factor/Kruppel-like factor 3 and its co-repressor C-terminal- binding protein 2.Journal of Biological Chemistry.2003Turner J,Nicholas H,Bishop D,Matthews J M,Crossley M.The LIM protein FHL3...
Whole-cell extracts (1 000 μg) isolated from ATDC5 chondrocyte-like cells or COS-7 cells overexpressing Pinch1 were incubated with 3 μg Smad2/3 antibody overnight at 4 °C with gentle rocking. The immune complexes were collected by the addition of 25 μL of protein A/G Magne...
We examined the expression of the LIM-domain protein cysteine- and glycine-rich protein 2 (CRP2) during transdifferentiation, a protein which in smooth muscle cells is associated with the cell skeleton as well as located in the nucleus3,4.Results:An increase of CRP2 was detectable by Western...
1) LIM domain LIM结构域1. The LIM domain is found in a wide variety of eukaryotic proteins that regulate gene expression and cell differ-entiation during development. 通过BLAST分析发现该基因编码的家蚕肌肉LIM蛋白,含有5个保守的LIM结构域,家蚕的另一种LIM蛋白(AAR23823)含一个LIM结构域,两者可能是...