The Lim domain and actin-binding protein 1 (LIMA1) is cytoskeleton-associated protein that inhibits actin filament depolymerization and cross-links filaments in bundles and is downregulated in some cancer cell lines (1,2). LIMA1 is also a key molecule linking the cadherin-catenin complex to the...
蛋白描述: LIM domain and actin-binding protein 1 isoform 1 [Homo sapiens] 蛋白大小: 760 aa 蛋白序列: messpfnrrqwtslslrvtakelslvnknkssaiveifskyqkaaeetnmekkrsntenl sqhfrkgtltvlkkkwenpglgaeshtdslrnssteirhradhppaevtshaasgakadq eeqihprsrlrsppealvqgryphikdgedlkdhsteskkmenclgesrhevekseisen tdasgkie...
LIM domain and actin-binding protein 1 (LIMA1), as an important actin cytoskeletal regulator, was initially thought to be a tumor suppressor frequently downregulated in epithelial tumors. Importantly, the deficiency of LIMA1 may be responsible for dysregulated cytoskeletal dynamics, al...
Protein Name:LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm) Human Gene Id:51474 Swiss-Prot:Q9UHB6 Formulation:Liquid in PBS containing 50% glycerol, and 002% sodium azide Source:Rabbit Purification:The antibody was affinity-purified from rabbit antiserum by affinity-...
肿瘤上皮蛋白丢失(Epithelial protein lost in neoplasm,EPLIN)又名LIM结构域和肌动蛋白结合蛋白1(LIM domain and actin binding 1,LIMA1),它是一种肌动蛋白相关分子,与乳腺癌、前列腺癌、食道癌、肺癌等各种癌症的发展和进展有关。顾名思义,随着癌症的进展,EPLIN的表达经常会丢失。EPLIN在肌动蛋白动力学的调节...
LIM domain and actin-binding protein 1 recombinant protein epitope signature tag (PrEST) 应用 All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org)and as a result, are supported by the most extensive characte...
LIM domain and actin binding 1 应用 All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org)and as a result, are supported by the most extensive characterization in the industry. ...
ABLIM1 (actin-binding LIM protein 1) is a member of the LIM-domain protein family, mediating interactions between actin filaments and cytoplasmic targets. ABLIM1 has been reported as a cell cortex protein specifically in non-erythrocytes, and is critical for the formation of dense interwoven cor...
In this study, we employed an unbiased tandem mass spectrometry-based strategy and discovered that the tumour suppressor LIM domain and actin-binding protein 1 (LIMA1), also known as epithelial protein lost in neoplasm (EPLIN), are novel API2–MALT1 interactors. We further show that LIMA1a ...
In this study, we employed an unbiased tandem mass spectrometry-based strategy and discovered that the tumour suppressor LIM domain and actin-binding protein 1 (LIMA1), also known as epithelial protein lost in neoplasm (EPLIN), are novel API2–MALT1 interactors. We further show that LIMA1α...