- 《Journal of Biological Chemistry》 被引量: 69发表: 1989年 Ligands of the colchicine site of tubulin: A common pharmacophore and new structural classes Structure-activity relationships for ligands of the colchicine site of tubulin were analyzed based on their common pharmacophore. The role of ...
(CACHE), a public benchmarking project, has garnered attention from the computational chemistry community and pharmaceutical industry for enhancing small-molecule hit-finding algorithms2. However, the hit-to-lead optimization process is still largely driven by hypotheses and depends on the experience ...
Using a mutant in which a permease domain of the transporter was disrupted, by growth analysis and epifluorescence microscopy, we confirmed peptide uptake via the Ami permease and intracellular location in the pneumococcus. By RNA-sequencing we found that the peptides modulated expression of genes ...
Specially, the representative sensing cases in aqueous or biological medium are all presented in recent five years to elucidate the importance of surface chemistry. The proposed sensing mechanisms are also discussed in these cases. Finally, a short outlook on the limitations and prospects of QD-...
- 《Inorganic Chemistry》 被引量: 268发表: 2005年 Stereochemistry of Compounds with Coordination Number Ten The stereochemistry of ten-coordinate rare-earth and transition-metal compounds is studied from the point of view of continuous shape measures (CShM) and d... A Ruiz‐Martínez,S Alvarez ...
https://ror.org/02zp2tc18grid.465326.00000 0004 0397 3932G.A. Krestov Institute of Solution Chemistry of the Russian Academy of Sciences 153045 Ivanovo RussiaE. S. Yurinahttps://ror.org/02zp2tc18grid.465326.00000 0004 0397 3932G.A. Krestov Institute of Solution Chemistry of the Russian ...
The Division of Chemical Physics and Nano-Lund, Lund University, Lund, 22100, Sweden Yang Liu (刘旸), Weihua Lin (林炜铧), Tonu Pullerits & Kaibo Zheng (郑凯波) Ångström Laboratory, Department of Chemistry, Uppsala University, Uppsala, 75120, Sweden ...
- 《Coordination Chemistry Reviews》 被引量: 450发表: 2003年 All-Electron Scalar Relativistic Basis Sets for Third-Row Transition Metal Atoms. A family of segmented all-electron relativistically contracted (SARC) basis sets for the elements Hf-Hg is constructed for use in conjunction with the ...
1). Nb–ligand conjugates were prepared using recombinant Nb expression, site-specific labeling, peptide synthesis, and click chemistry (Fig. 1B). All peptides, including PTH1-11-6E, which contains a six-carbon linker (6-aminohexanoic acid, Ahx) between components, were synthesized using ...
The mode of bond activation occurring in TS5 has the potential to contribute to the enrichment of two research topics that have long been contemplated in synthetic chemistry: (1) transition metal-catalyzed carbon–carbon bond activation37,38,39,40 in which the cleavage of C–C bonds with catal...