Structure-Based and Ligand-Based Drug Design for HER 2 Receptor[J] . Hung-Jin Huang,Kuei-Jen Lee,HsinWei Yu,Chien-Yu Chen,Chih-Ho Hsu,Hsin-Yi Chen,Fuu-Jen Tsai,CalvinYu-Chian Chen.Journal of Biomolecular Structure and Dynamics . 2010 (1)...
The BioPharmics platform's cutting edge ligand- and structure-based drug design methods, enable fast, accurate & robust 3D modelling.
In a lot of cases, ligand-based drug design and structure-based drug design can be applied together to develop potent drug candidates. These methods have been applied in different stages and aspects in the research and development at HitGen and benefitted multiple projects....
1) Ligand-based drug design 基于配体的药物设计2) substrate based design 基于底物的药物设计 1. In recent years, three methods of molecular design have been developed, including substrate based design,structure based design and combinatorial chemistry technology. 近年来 ,科学家们发展了三种分子设计...
drug design- structure and ligand-based appraoches. (kenneth merz etl.) 药学 药物化学 第7页 小木虫 论坛
State-of-the-art, structure-based method for assessing the energetics of water solvating ligand binding sites for ligand optimization Life Science Phase An easy-to-use pharmacophore modeling solution for ligand- and structure-based drug design Life Science Prime A powerful and innovative solution...
Successful drug discovery often requires optimization against a set of biological and physical properties. We describe de novo design studies that demonstrate successful scaffold hops between known classes of ligands for p38 MAP kinases using ligand-based and structure-based multi-parameter scoring function...
LEA3D: A Computer-Aided Ligand Design for Structure-Based Drug Design LEA3D: a computer-aided ligand design for structure-based drug design. Douguet,D.,Munier-Lehmann,H.,Labesse,G.,Pochet,S. Journal of Medicinal ... 被引量: 0发表: 2005年 e-LEA3D: a computational-aided drug design ...
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drug design- structure and ligand-based appraoches. (kenneth merz etl.) 药学 药物化学 第6页 小木虫 论坛