LiverGut microbiotaEmpagliflozin is currently known to decrease blood glucose levels, delay renal failure, and reduce the risk of cardiovascular death and all-cause mortality in patients with type 2 diabetes with cardiovascular disease. However, the effects of empagliflozin on the lifespan and health ...
Erythrocyte life span in patients with chronic renal failure decreases with progressive severity of uremia and may be reduced to one-third of normal (116). Early experiments, in which red cell survival was found to normalize when cells from uremic patients were transfused into nonuremic recipients...
In thrombocytopenia, because of defective production of platelets, the lifespan should be normal, provided that platelets are not being lost by bleeding during the course of the study. In thrombocytopenia associated with splenomegaly, the recovery of injected labelled platelets is low, but their ...
To evaluate circuit lifespan (CL) and bleeding risk during continuous renal replacement therapy (CRRT), in combined liver and renal failure. Single-center retrospective analysis of adults with acute liver failure or decompensated cirrhosis who received CRRT, without anticoagulation or with heparinization...
K. Huber1, S. Dänicke2, J. Rehage3, H. Sauerwein4, W. Otto5, U. Rolle-Kampczyk6 & M. von Bergen5,6,7 The failure to adapt metabolism to the homeorhetic demands of lactation is considered as a main factor in reducing the productive life span of dairy cows....
Xinhua Shu1, Dafni Vlachantoni1, Roderick R McInnes3 & Rudolph A Riemersma4 We examine the allometric (comparative scaling) relationships between rates of neurodegeneration resulting from equivalent mutations in a diverse group of genes from five mammalian species with different maximum lifespan potentia...
Self-management includes all behavioural measures and cognitive activities aimed at coping with challenges arising throughout the lifespan. While virtually all of these challenges can be met without pharmacological means, alcohol consumption has long bee
NAD(+) repletion improves mitochondrial and stem cell function and enhances life span in miceAdult stem cells (SCs) are essential for tissue maNSTL... - 《Science》 被引量: 0发表: 2016年 NAD(+) repletion improves mitochondrial and stem cell function and enhances life span in mice Ryu, Y...
K. Stressful early life experiences and immune dysregulation across the lifespan. Brain Behav. Immun. 27, 8–12 (2013). Article CAS PubMed Google Scholar Slavich, G. M., Way, B. M., Eisenberger, N. I. & Taylor, S. E. Neural sensitivity to social rejection is associated with ...
This Review covers the current status and controversies surrounding the potential of sirtuins as novel pharmacological targets, with a focus on SIRT1. Abstract Although the increased lifespan of our populations illustrates the success of modern medicine, the risk of developing many diseases increases ex...