Forty-eight cases of Trisomy 18 were identified, five at amniocentesis. Four of the 43 clinical cases (9%) were mosaics. The median life expectancy for live-born infants was five days (range one hour to 18 month
Life expectancy can be very short—within minutes or hours of birth (e.g. Edwards’ syndrome (trisomy 18)) – through to the likelihood of death occurring sometime during the childhood years or adulthood (e.g. Duchenne muscular dystrophy; severe cerebral palsy) [18,19,20]. Given the ...
With increased life expectancy, the incidence of neurodegenerative disease is expected to grow. By 2025, AD will affect as many as a million Canadians, and by 2050, this number will double. Sporadic AD, ALS, and PD/LBD are all associated with neural accumulation of pathological multimers of ...
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