Despite these observations, life expectancy of hemophilia patients has remained mostly unchanged - 67 vs. 66 and 68 years and in patients with severe disease decreasing from 63 to 59 years. Given what we consider to be major advances in hemophilia treatment and care over the past 2 decades, ...
Treatment of patients with hemophilia has advanced over the past decades, but it is unknown whether this has resulted in a normal life expectancy in the Netherlands. OBJECTIVE This observational cohort study aimed to assess all-cause and cause-specific m...
Mortality, life expectancy and causes of death of persons with hemophilia in the Netherlands 2001‐2018 Introduction and objectives: Cause of mortality in patients with chronic liver diseases (CLDs) may differ based on underlying etiology of liver disease. Ou... S Hassan,R Monahan,EPM Bunschoten...
In fact, with today’s treatments and understanding of the triggers for symptoms, patients can often live complete lifestyles with no impact on life expectancy. This can be huge for convincing life insurance companies to consider lupus patients for affordable plans. ...
Life-expectancy for example is improving quicker for more educated people (Van Oyen 2010). This situation is persisting despite the famous quality of social insurance in place for... V Tellier,A Vandenhooft - 《European Journal of Public Health》 被引量: 0发表: 2014年 The EU Non-life ...
Hemophilia is an example of a serious XLGD. This disorder is caused by the absence of a protein responsible for the clotting of blood. Lacking this protein, a person with hemophilia may easily bleed to death from simple cuts and injuries that would be of little danger to the average person...
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“unprotected X chromosome” theory. Males are the heterogametic sex and are vulnerable to a variety of X-linked diseases, where only a single loss of function mutation is needed for diseases such as hemophilia, Lesch Nyhan syndrome, and muscular dystrophy. Females are mosaics, with stochastic ...
For nearly a third of patients with hemophilia A and almost all patients with Pompe disease, their own immune system is their greatest obstacle to treatment. When given essential proteins and enzymes, their body perceives the treatments as a threat and a
Intracranial bleeding and malignancies were the most common causes of death. Estimated median life expectancy of patients with hemophilia was 77 years, six years lower than the median life expectancy of the general Dutch male population (83 years). Over the past 45 years, death rates of patients...