Selection-adjusted comparison of life-expectancy of patients on continuous ambulatory peritoneal dialysis, haemodialysis and renal transplantation. Lancet 1987; 1: 1115–19.Burton PR, Walls J: Selection-adjusted
The impact of genetic variation on overall disease burden has not been comprehensively evaluated. We introduce an approach to estimate the effect of genetic risk factors on disability-adjusted life years (DALYs; ‘lost healthy life years’). We use genetic information from 735,748 individuals and ...
Abeta has been detected in the blood and CSF of AD patients and in normal controls (6). Abeta is also present in vascular and plaque amyloid filaments in trisomy 21 (Down's syndrome), hereditary cerebral hemorrhage with amyloidosis (HCHWA)-Dutch type, and normal brain aging (Mori, H et...
[102]. The average life expectancy of EGCG increased by 13.1%, 8.0% and 11.8% at 0.1–10.0 μg/mL, respectively, under 35 °C high temperature stress. Under oxidative stress, EGCG increased the average lifespan ofnematodesby 172.9%, 177.7% and 88.5% at 0.1–10.0 μg/mL, respectively....
Examples of extrinsic cardiomyopathies include: Amyloidosis can infiltrate heart cells with amyloid protein. Sarcoidosis can cause heart cell inflammation. Viral infections may cause inflammation of heart muscle (myocarditis) with temporary or potentially permanent damage to heart muscles cells leading to ...
Primary (AL) amyloidosis, now the more commonly seen form of the disorder, usually has a poor prognosis and short life expectancy [2]. Colchicine, which effectively prevents acute fibril attacks in patients with familial Mediterranean fever (FMF), a condition that predisposes to amyloidosis, has ...