We analyzed 851 The Cancer Genome Atlas whole-transcriptome sequencing (WTS) data to investigate EBV infection by life cycle information using three-step LiEB workflow: 1) characterize virus infection generally; 2) align transcriptome sequences against a hybrid human-EBV genome, and 3) quantify EBV...
FIG 1. Induction of the EZH2 gene by Epstein-Barr virus (EBV) infection in primary B cells. (A) B cells isolated from peripheral blood mononuclear cells from a healthy donor were sorted using FACSAria II and infected or mock infected with WT EBV at a multiplicity of infection of ∼1....
Epstein–Barr virusHerpesviridaeCD21andMHC-II Herpes simplex virus 1/2HerpesviridaeNectin-1/2orHVEM Influenza AOrthomyxoviridaeSialic acid HenipavirusParamyxoviridaeNephrin B2 Measles virusParamyxoviridaeSLAMorNectin-4 BunyavirusPhleboviridaeDC-SIGN Enterovirus 71PicornaviridaePSGL-...
Epstein-Barr virus (EBV) is a human herpesvirus with a DNA genome of about 165 kbps [11]. Many known strategies of EBV mimic cellular processes and principles as the virus has coevolved with its human host. EBV has copied central mechanisms of the cell, e.g., receptor signaling, DNA re...
After the primary infection, that may or may not cause infectious mononucleosis, the ubiquitous Epstein–Barr virus (EBV) is carried for lifetime. The great majority of adult humans are virus carriers. EBV was discovered in a B-cell lymphoma (Burkitt lymphoma). EBV infection in humans is the...
Epstein-Barr virus has developed multiple strategies to ensure its long-term persistence in the infected B cells of immunocompetent hosts. These include the establishment of cell-phenotypespecific programs of viral gene expression and the transduction of cellular genes that modulate immune responses. Cyt...
Qu. 1999. Natural history of Epstein-Barr virus load in pediatric thoracic recipients with post transplant lymphoproliferative disorders and other primary EBV infections. Transplantation 67 : 215.Webber SA, Rowe DT, Boyle GJ, et al. Natural history of Epstein-Barr virus load in pediatric th...
, Epstein-Barr virus), surgery, or emotional trauma. Remember, my fibromyalgia followed low-back surgery. Besides the widespread muscle pain, there are a myriad of other conditions that often occur with fibromyalgia. (I've denoted symptoms I've experienced with exclamation (!) marks). These ...
papilloma virus (HPV),causing cervical and oropharynx cancers; Infections by theEpstein-Barr virus (EBV), causing lymphomas and nasopharyngeal cancer;Merkel cell polyomavirus, causing Merkel cell carcinomas;Human T-cell lymphotropic virus, causing leukemias; andFusobacterium, associated with colorectal ...
Epstein-Barr virus (EBV) is a human gamma herpes virus that infects B cells and induces their transformation into immortalized lymphoblasts that can grow as cell lines (LCLs) in vitro. EBNA-3 is a member of the EBNA-3-protein family that can regulate transcription of cellular and viral gen...