Lidocaine anesthetic is a local anesthetic injection administered before painful medical procedures to numb specific body regions. Lidocaine anesthetic preventspainby blocking the nerves in the treatment area from sending painsignals to the brain. Lidocaine stabilizes the membrane of nerve cells (neurons) ...
The tissue oxygenation index (TOI) in the skin near the mental foramen on the blocked side was recorded using near-infrared spectroscopy at 15 minutes after the local anesthetic injection.ResultsOne participant did not complete the study...
The injection volume was 5 µL. The time of analysis was 10 min, and the retention time was 4.2 min. According to the EMA guidelines [44], IVRT serves as an effective method for evaluating the release rate and extent of the active ingredient in formulations. The key parameters determined...
Oraqix used at the recommended doses is not likely to cause toxic plasma levels of lidocaine or prilocaine. However, if other local anesthetics are administered at the same time, e.g. topically or by injection, the toxic effects are thought to be additive and could result in an overdose wi...