Lichen sclerosus is suspected to have a genetic component due to a strong association with family history and is associated with various autoimmune diseases. Treatment involves medium- and high-potency topical corticosteroids, as well as calcineurin inhibitors; however, the optimal treatment regimen is ...
Conclusions Tretinoin 0.025% cream applied for 24 weeks may represent a useful alternative option to corticosteroids in the treatment of active VLS, acting particularly on hyperkeratosis and pallor. 展开 关键词: vulvar lichen sclerosus topical tretinoin active treatment efficacy safety ...
Diagnosis is made with vulvar biopsy. Treatment is important and the regimen most often includes topical corticosteroid ointments. Lifetime surveillance of the skin is imperative because of the increased risk of squamous cell carcinoma in patients with lichen sclerosus....
Treatment of vulvovaginal lichen planus with vaginal hydrocortisone suppositories Curr. Infect. Dis. Rep., 4 (2002), pp. 507-508 CrossrefGoogle Scholar [5] S.M. Cooper, I. Ali, M. Baldo, F. Wojnarowska The association of lichen sclerosus and erosive lichen planus of the vulva with aut...
(8-methoxypsoralen) in a dilute bathwater solution may be applied to the skin before UV-A.2A PUVA-bath photochemotherapy regimen has been shown to be an elegant alternative in the treatment of psoria- sis.2,3We describe our first four patients with LP who received PUVA-bath photo...
As the recurrence rate of active lichen sclerosus in prepubertal girls treated with topical corticosteroids is high, and the majority of prepubertal girls with lichen sclerosus continue to have disease after menarche, a treatment regimen that does not rely on corticosteroids may be beneficial....
Lichen sclerosus et atrophicus in sclerodermatous chronic graft-versus-host disease. Int J Dermatol 1999; 38:708-11.Cordoba S, Vargas E, Fraga J, Aragues M, Fernandez-Herrera J, Garcia-Diez A. Lichen sclerosus et atrophicus in sclerodermatous chronic graft-versus-host dis- ease. Int J ...
vulvar lichen sclerosustopical tretinoinactive treatmentefficacysafetyObjective To assess the effectiveness and safety of a 24-week application of tretinoin 0.025% cream, with an alternate-day regimen, in achieving control of VLS signs and symptoms. Methods 17 patients affected with VLS were included. ...
treatment regimenBackgroundTopical corticosteroids are the first-line treatment for vulvar lichen sclerosus (VLS). However, evidence on the most appropriate treatment regimen is lacking.ObjectivesTo compare the effectiveness and tolerability of tapering vs. continuous application of mometasone furoate (MMF)...
The scheme combining MMF and CC was better tolerated than the combination of MMF and T.The combination with a topical retinoid did not enhance the effectiveness of a potent corticosteroid in the treatment of VLS. Either the scarce efficacy of the short-contact therapy regimen or a less ...