(redirected fromGenomic library) Medical Related to Genomic library:CDNA library,nucleic acid probe ge·nome (jē′nōm′) n. 1.The total genetic content contained in a haploid set of chromosomes in eukaryotes, in a single chromosome in bacteria or archaea, or in the DNA or RNA of viruses....
DNA deoxyribonucleic acid: an extremely long, double-stranded nucleic acid molecule arranged as a double helix that is the main constituent of the chromosome and that carries the genes as segments along its strands: found chiefly in the chromatin of cells and in many viruses. ...
For next generation DNA sequencing, we have developed a rapid and simple approach for preparing DNA libraries of targeted DNA content. Current protocols for preparing DNA for next-generation targeted sequencing are labor-intensive, require large amounts of starting material, and are prone to artifacts...
Such a plasmid is said to contain a genomic DNA clone, and the entire collection of plasmids is called a genomic DNA library. But because the genomic DNA is cut into fragments at random, only some fragments contain genes. Many of the genomic DNA clones obtained from the DNA of a higher ...
In addition, using a single DNA probe to screen the traditional library is a simple precursor to the common procedure of using a panel of probes to do whole exome sequencing. After cloning all the possible genes from an organism into a library, the next step is to identify the genes of ...
Construction of a GBS〨AS DNA subtraction library allows discovery of previously unidentified GBS genes and rapid location of unique regions on the GBS chr... Construction of a GBS〨AS DNA subtraction library allows discovery of previously unidentified GBS genes and rapid location of unique regions ...
Characterization of a cDNA library, enriched for fragments of genes preferentially expressed in the embryonic day 14.5 mouse forebrain as compared to the adult forebrain, was performed using DNA sequencing and in situ RNA hybridization to sections of mouse embryos. One hundred and thirty different ...
The GenBank(R) sequence database (http://www. ncbi.nlm.nih.gov/ ) incorporates DNA sequences from all available public sources, primarily through the direct submission of sequence data from individual laboratories and from large-scale sequencing pro- jects. Most submitters use the BankIt (WWW...
Crop pathogens greatly reduce agricultural productivity and are a persistent threat to global food security4,5. The most effective and sustainable approach to mitigate crop disease is through breeding of resistance (R) genes into crop varieties. MostRgenes encode immune receptors, such as nucleotide-...
Preprocessing: We provide rich preprocessing functions such as normalization, dimension reduction, and gene filtering. Take graph-sc model as an example, we filter out the rarely expressed genes and normalize the remaining to obtain the same total count for each cell. Then, only the highly express...