LHRH agonists and antiandrogens in prostate cancer . In: Ratliff TL , Catalona WJ , eds. Genitourinary Cancer . Boston: Martinus Nijhoff; 1987 : 157 – 200 .Labrie F, Dupont A, Belanger A: LHRH agonist and antiandrogens in prostate cancer, In Ratliff TL, Catalona WJ (Eds): ...
[2] Labrie F , Dupont A , Belanger A , et al. Flutamide eliminates the risk of disease flare in prostatic cancer patients treated with a luteinizing hormone-releasing hormone agonist.[J]. Journal of Urology, 1987, 138(4 Part 1):804-806. [3] Sh...
Moul, JW (2012) Prostate cancer: Making the switch from LHRH antagonist to LHRH agonist. Nat Rev Urol 9: pp. 125-126Moul JW. Prostate cancer: making the switch from LHRH antagonist to LHRH agonist. Nat Rev Urol 2012;9(3):125-126....
The product is the only LHRH (luteinising hormone releasing hormone) agonist with the innovative, controlled-release ATRIGEL Delivery System. TOLMAR Pharmaceuticals receives FDA label update approval for ELIGARD prostate cancer drug This is also proven by the fact that treatment of hypothyroid infertile...
Prostate cancerHormone therapyLHRH agonistEligard®Testosterone suppressionBreakthrough responseAcute-on-chronic responseCastration levelFollowing the discovery that prostate tumour growth is androgen-dependent, androgen suppression as achieved with orchiectomy (standard of castration) has been shown to delay ...
forms. LHRH-(1–5) have contrasting effects from its parent peptide, LHRH-I, could help explain the lack of correlation between the action of LHRH-I analogs that behave as antagonists at the pituitary level but result in agonist-like anti-proliferative effects in many cancers 4, ,5....
ChEBI: Gonadorelin is a ten-membered synthetic oligopeptide comprising pyroglutamyl, histidyl, tryptophyl, seryl, tyrosyl, glycyl, leucyl, arginyl, prolyl and glycinamide residues joined in sequence. It has a role as a gonadotropin releasing hormone agonist. It is an oligopeptide and a peptide horm...
9 RegisterLog in Sign up with one click: Facebook Twitter Google Share on Facebook Dictionary Medical Wikipedia Related to LHRH:goserelin,LHRH agonist,LHRH analogue AcronymDefinition LHRHLuteinizing Hormone-Releasing Hormone(produced in hypothalamus) ...
I. Methods for Treating Prostate Cancer The methods of the invention feature the administration of an LHRH-R antagonist in combination with a second therapy, such as performance of a procedure that removes or destroys tumor tissue or administration of an LHRH-R agonist. One aspect of the inv...
结果:LHRH 类似物的药理作用较为广泛,其剂型主要为埋植剂和微球,二者相比,微球制剂具有更大的优势。结论:LHRH类似物微球制剂必将拥有更大的应用前景。[关键词] 促黄体生成激素释放激素;激动剂;拮抗剂;埋植剂;微球[中图分类号]R944.9; R977 [文献标识码]A[文章编号]Advances in luteinizing hormone-...