Our results show that LHCG receptor is expressed in the spongious and cavernous tissue of the human penis. This finding suggests that LH can affect the spongious and cavernous tissue in human and play a significant role in the development of erectile dysfunction among the aging men....
L-selectin is a lectin-like receptor that mediates the attachment of lymphocytes to high endothelial venules (HEV) of lymph nodes during the process of lym... Hemmerich,S. - 《Journal of Experimental Medicine》 被引量: 572发表: 1994年 Global vascular expression of murine CD34, a sialomucin-...
Introduction Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that affects mostly women in reproductive age. Consequently, the sex hormones with immunosuppressive effects and their receptors could play an important role for the autoimmune disease onset and progress. Therefore, the ...
sex steroid receptorKuroda H, Konishi I, Mandai M, Nanbu K, Rao Ch V, Mori T. Ovarian cancer in infertile women during or after ovulation-induction therapy: expression of LH/hCG receptors and sex steroid receptors. Int J Gynecol Cancer 1997; 7: 451457. A possible association between the ...
Reverse transcription-polymerase chain reaction (RT-PCR) analysis revealed that HCG/LH receptor was present in both cultured myometrial and leiomyomal cells. Treatment with HCG significantly increased cell proliferation in both myometrial and leiomyomal cells (P < 0.03), especially at an early ...
DIAGNOSIS AND THERAPY OF DISEASES RELATING TO A DISPROPORTION OF LUTEINIZING HORMONE/CHORIONIC GONADOTROPIN RECEPTOR (LHR; LHCGR) SPLICE VARIANTSThe present invention relates to a novel exon of the LHR, namely exon 6A, as well as to mutated forms thereof. Particularly, the present invention relates...
DIAGNOSIS AND THERAPY OF DISEASES RELATING TO A DISPROPORTION OF LUTEINIZING HORMONE/CHORIONIC GONADOTROPIN RECEPTOR (LHR; LHCGR) SPLICE VARIANTSThe present invention relates to a novel exon of the LHR, namely exon 6A, as well as to mutated forms thereof. Particularly, the pres...
GefitinibMethotrexateEctopic pregnancyMedical treatmentPhase IIEctopic pregnancies are a leading cause of maternal mortality. Most are treated surgically. We evaluated the efficacy and safety of combining oral gefitinib (epidermal growth factor receptor inhibitor) with methotrexate to treat larger ectopic ...