包括DLB和帕金森病伴(路易体)痴呆(Parkinson disease with dementia, PDD)的总称。越来越多的共识认为DLB是一种独特的临床疾病,其特点是早发痴呆、进展更快速。相比之下,PDD患者出现痴呆的时间要晚得多,有时甚至在帕金森病(Parkinson disease, PD)发病后10年才出现。虽然这两种疾病的临床特征和病理学类似,但临床对D...
包括DLB和帕金森病伴(路易体)痴呆(Parkinson disease with dementia, PDD)的总称。越来越多的共识认为DLB是一种独特的临床疾病,其特点是早发痴呆、进展更快速。相比之下,PDD患者出现痴呆的时间要晚得多,有时甚至在帕金森病(Parkinson disease, PD)发病后10年...
Prasad S, et al. Recent advances in Lewy body dementia: A comprehensive review. Dis Mon. 2023 May;69(5):101441. doi: 10.1016/j.disamonth.2022.101441. McKeith IG, et al. Diagnosis and management of dementia with Lewy bodies: Fourth consensus report of the DLB Consortium. Neurology. 2017 ...
Dementia with Lewy bodies (DLB) is a progressive, degenerative dementia of unknown etiology. Affected patients generally present with dementia preceding motor signs, particularly with visual hallucinations and episodes of reduced responsiveness. Signs and symptoms Symptoms and signs of DLB may result, in...
Dementia with Lewy bodies (DLB) is the second most common neurodegenerative dementia following Alzheimer disease. It stems from the formation of Lewy bodies, which contain aggregates of the misfolded protein, 伪-synuclein. These deposit in areas of the nervous system and brain, leading to neuronal...
Lewy body dementia (DLB) is a common form of cognitive impairment, accounting for 30% of dementia cases in ages over 65 years. Early diagnosis of DLB has been challenging; particularly in the context of differentiation with Parkinson’s disease dementia and other forms of dementias, such as Al...
Cortical lewy body disease (CLBD);Diffuse lewy body disease (DLBD);Lewy body dementia (LBD);Senile dementia of lewy type Definition Dementia with Lewy bodies (DLB) is a degenerative disorder characterized by progressive cognitive decline combined with three additional defining features: (1) pronounc...
这在某种程度上要归功于组织学技术的发展，特别是核小体表面蛋白免疫组化染色技术和最近的所有核素染色技术。使大脑皮层染色更为清晰可见。过去文献中曾用多种术语描述DLB，包括皮质路易体病（cortical Lewy boay disease）、老年痴呆路易体型（senile dementia of Lewy body type）和阿尔茨海默病路易体...
We have published several articles about dementia in the past. As everyone knows, the most common type of dementia is Alzheimer's disease. In this issue, we'll tackle about the second most common type of dementia called Lewy body dementia (LBD) or Dementia with Lewy bodies (DLB), of ...