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To test whether the NMO- IgG preparations I, III, and IV are also able to initiate astro- cyte destructive lesions in our rat model of experimental NMOSD [24], we injected these NMO-IgGs into Lewis rats after opening the blood-brain barrier of these animals with MBP-specific T cells. ...
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Furthermore, the mouse WISP-1 is identical to the gene identified as ELM1 (GenBank accession# AB004873). ELM1 is expressed in low, but not high, metastatic mouse melanoma cells, and suppresses the in vivo growth and metastatic potential of K-1735 mouse melanoma cells (Hashimoto et al, ...
maximize predictive value and minimize misclassification of cases and non-cases based on a balance between the sensitivity (i.e., the number of true cases detected) and the specificity (i.e., the accuracy) of a test. These two variables may also be considered positive predictive value and ...