The study flow diagram can be found in Fig. 1. The Newcastle-Ottawa Scale (NOS) was used for assessing the quality of the articles included [21]. This scale can lead to a maximum score of 9 for each individual study, with studies with increasing NOS being considered as having increased ...
with many studies implicating loss-of-function (LoF) mutations within these genes. Despite this, no significant clinical advances have been made so far in the development of therapeutics for ASD. Given the role of LoF mutations in ASD etiology, many of the therapeutics...
27,28,29,30,31. However, it is largely unknown ifS. mansonilncRNA levels may be regulated by drugs. In the present work, we have evaluated the effect of 5-AzaC on lncRNA
widely used in earlier and current biomechanical model studies of multi-joint systems such as the human spine is the consideration of the balance of net external moments only at a single cross section (typically at lowermost lumbar discs) rather than along the entire length of the spine. These...
IVD consists of the annulus fibrosus (AF), the nucleus pulposus (NP) and the cartilaginous endplate (CEP), which provides mobility and compressive resistance in the spine. At in vitro experiments, degenerative changes such as AF rupture, vascular formation, and degradation extracellular matrix (ECM...
Nearly all robotic systems were designed to accommodate a variety of procedures across different specialties (73%) (Fig. 4a). Orthopedic surgery was the fastest-growing specialty in surgical robotics, with 33% of all new robotic systems introduced since 2015 intended for spine, knee, and hip sur...
Insert with the same diagram indicates the distribution of C/AD and AD samples. e Quantitation and statistical analysis of the levels of KIF5 family members in females and males from AD and C/AD samples. f Spearman’s correlation analyses for age and the levels of KIF5 members in AD and...
Fig. 3: Diagram of inhibitory antisense oligonucleotide (ASO) mechanisms. AASOs can be used in the inhibition of the upstream start codon within the upstream open reading frame (uORF) of an mRNA transcript to increase translational expression of the target gene;BASOs can be used to target and...
Graduate Program in Functional Performance and Rehabilitation, Federal University of the Jequitinhonha and Mucuri Valleys, Diamantina 39100-000, Brazil 3 MATériaux et Ingénierie Mécanique, Université de Reims Champagne Ardenne, 51100 Reims, France ...
Department of Dermatology, Xiangya Hospital, Central South University, Changsha 410008, China 2 Department of Spine Surgery, Xiangya Hospital, Central South University, Changsha 410008, China 3 National Clinical Research Center for Geriatric Disorders of Xiangya Hospital, Central South University (Sub-cent...