The locus for hyperekplexia has been mapped to 5q32, a region known to possess several neurotransmitterreceptor genes. One such gene codes for the ligand-binding α1subunit of the glycine receptor. Six different mutations within the α1subunit have been identified. The residue is located at th...
A diagnosis of myelopathy was established based on the presence of hyperreflexia, including a positive Hoffmann sign, upper extremity sensory disturbance and obvious MRI-documented cervical spinal cord compression. Sensory and motor nerve conduction velocities in the peripheral nerves were within normal ...
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The patient was discharged on the fifteenth hospital day and has remained without further symptoms for 1 year. 356 PARAPLEGIA Discussion TeA's interfere with autonomic neurotransmission by at least three mechanisms: peripheral and central anticholinergic action; blockade of the re-uptake of ...