The use of intravital microscopy technique allows direct in vivo assessment of leukocyte rolling and adhesion on cortical meningeal vessels. The current review highlights the use of intravital microscopy and its association with neuroinflammatory parameters in different models of experimental brain diseases ...
functional alterations relevant to VAD trauma are still unclear. If NPSS induces shedding of the importantadhesion receptorson leukocytes’ surface, it could compromise the leukocyte rolling and adhesion on inflamedendothelial cellsand reduce leukocyte transmigration capacity and bactericidal ability, which ...
activation, and adhesion of individual leukocytes in vitro. Object-oriented software components were designed, verified, plugged together, and then operated in ways that represent the molecular and cellular mechanisms believed responsible for leukocyte rolling and adhesion. The result is an in ...
摘要: Background: Recently, it has become apparent thatreactive oxygen species (ROS) play a critical role in the initiation ofatherosclerosis. In this study, the effect of radical scavenger edaravone tothe leukocyte rolling and to the expression of adhesion...关键词:...
Leukocyte rolling and adhesion are generally observed in venules but rarely observed in arterioles. With the use of intravital microscopy, we found that a 4-h treatment with interleukin-1beta (IL-1beta) and tumor necrosis factor-alpha (TNF-alpha) dose dependently induced leukocyte rolling and ad...
BjcuL (1.25-10µg/30µl) potential was investigated for leukocyte rolling and adhesion to endothelial cells in living microvessels using intravital microscopy, which showed that it induced a dose-dependent increase in rolling and adherence of leukocytes, acting directly on endothelial cells of ...
or a nitric oxide (NO) donor (CAS-1609, 10 microM superfusion) markedly attenuated LPC-induced leukocyte rolling and adherence (P < 0.01 from LPC alone). Immunohistochemical localization of P-selectin and intercellular adhesion molecule-1 (ICAM-1) expression on mesenteric venules was significantly...
normal leukocyte rolling but have a pronounced defect in MCP-1-induced leukocyte firm adhesion to microvascular endothelium and reduced leukocyte extravasation... WA Kuziel,SJ Morgan,TC Dawson,... - 《Proceedings of the National Academy of Sciences of the United States of America》 被引量: 1321...
1) leukocyte rolling 白细胞滚动1. Effects of recombinant human interleukin 1α on leukocyte rolling and adhesion in rat spinotrapezius muscle preparation; 重组人白介素-1对大鼠微血管白细胞滚动与粘附的作用2) leukokinesis 白细胞移动3) leukocyte movement 白细胞运动 1. The primary study of ...
P. and Kubes,S Kanwar - 《Journal of Immunology》 被引量: 716发表: 1994年 The alpha 4-integrin supports leukocyte rolling and adhesion in chronically inflamed postcapillary venules in vivo. A role for the alpha 4-integrin (alpha 4 beta 1 or alpha 4 beta 7), has been implicated in the...