Analysing the relevance of the PHD isoforms for kidney development, it was demonstrated thatPhd2deletion in FOXD1-expressing renal stroma cells (Foxd1-Cre) does not affect nephrogenesis [72]. Combined deletion of bothPhd2andPhd3, however, led to abnormal development of the kidney [72]. In ...
doi:10.1057/9781137394507_7Robert DeFillippiColette DumasSushil BhatiaPalgrave Macmillan US
Lessons Learned from an Attempted Pragmatic Randomized Controlled Trial for Improvement of Chronic Pain-Associated Disability in Green Professions: Long-Term Effectiveness of a Guided Online-Based Acceptance and Commitment Therapy (PACT-A) 2022, International Journal of Environmental Research and Public Heal...
We performed a pilot study for systematic transfer of molecularly “unsolved” exomes from the clinical environment to a research setting, in order to potentially fuel human genetic disease gene discovery. The WES data from 74 probands for whom clinical singleton WES did not reveal a secure molecu...
Alvin Zipursky Editor-in-Chief Genetic Regulation of Branching Morphogenesis: Lessons Learned from Loss-of-Function Phenotypes MING CHANG HU AND NORMAN D. ROSENBLUM Program in Developmental Biology, Research Institute, The Hospital for Sick Children, and Division of Nephrology, Departments of ...
it is patent how Melchizedek put his new understanding into practice. Alas, the text does not offer evidence of Abram’s change of heart. Rabbi Meir’l (as presented by the narrator of the tale) also did not expand on this point, merely stating, “And Abraham learned from Shem the son...
Development of PI3K inhibitors: lessons learned from early clinical trials. Nature Rev. Clin. Oncol. 10, 143–153 (2013). Article CAS Google Scholar Klempner, S. J., Myers, A. P. & Cantley, L. C. What a tangled web we weave: emerging resistance mechanisms to inhibition of the ...
The primary electrophysiological changes and the mechanisms of arrhythmogenesis associated with HF depend on the etiology [2]. However, there are some common features, which are described in this section. At the cellular level, there is a prolongation of the action potential, resulting from the ...
Without a vaccine available, three lessons from the 1918 Spanish flu pandemic may arm us in our fight against COVID-19. First, those who survived the first wave developed immunity to the second wave, highlighting the potential of passive immunity-based treatments like convalescent plasma and cell...
Biotechnol Biofuels (2016) 9:144 DOI 10.1186/s13068-016-0548-4 Biotechnology for Biofuels RESEARCH Open Access Lessons learned from the microbial ecology resulting from different inoculation strategies for biogas production from waste products of the bioethanol/sugar industry Athaydes ...